289037-48-5

Basic information

• Product Name: 3-AZA-BICYCLO[3.1.0]HEXAN-6-YLMENTHOL
• Synonyms: 3-AZA-BICYCLO[3.1.0]HEXAN-6-YLMENTHOL;(3-Azabicyclo[3.1.0]hex-6-yl)methanol;3-Azabicyclo[3.1.0]hexane-6-methanol;3-aza-bicyclo[3.1.0]hexan-6-ylMethanol
• CAS NO: 289037-48-5
• Molecular Formula: C₆H₁₁NO
• Molecular Weight: 113.16
• Mol File: 289037-48-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 203℃
• Flash Point: 110℃
• Appearance: /
• Density: 1.108
• Vapor Pressure: 0.071mmHg at 25°C
• Refractive Index: 1.513
• PKA: 14.94±0.10(Predicted)
• CAS DataBase Reference: 3-AZA-BICYCLO[3.1.0]HEXAN-6-YLMENTHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AZA-BICYCLO[3.1.0]HEXAN-6-YLMENTHOL(289037-48-5)
• EPA Substance Registry System: 3-AZA-BICYCLO[3.1.0]HEXAN-6-YLMENTHOL(289037-48-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 289037-48-5(Hazardous Substances Data)

Usage

General Description

3-AZA-BICYCLO[3.1.0]HEXAN-6-YLMENTHOL is a chemical compound that belongs to the class of organic compounds known as menthols. These are aromatic compounds containing a cyclohexane ring substituted with a methyl group and a hydroxyl group at adjacent positions, and with one double bond. The exact properties of this specific compound, including its physical characteristics or potential uses, are not widely documented in scientific literature as it is quite specific and niche. As with all chemicals, it should be handled with caution using appropriate safety measures.

InChI:InChI=1/C6H11NO/c8-3-6-4-1-7-2-5(4)6/h4-8H,1-3H2/t4-,5+,6+

Upstream product

• 871727-08-1 (3-benzyl-3-azabicyclo[3.1.0]hexan-6-yl)methanol 

Downstream Products

• 850808-56-9 benzo[b]thiophene-2-carboxylic acid [3-(4-ethyl-benzyl)-3-aza-bicyclo[3.1.0]hex-6-ylmethyl]-(3-fluoro-4-morpholin-4-yl-phenyl)-amide 
• 850808-54-7 (3-(4-ethyl-benzyl)-3-aza-bicyclo[3.1.0]hex-6-ylmethyl)-(3-fluoro-4-morpholin-4-yl-phenyl)-amine 
• 1144092-90-9 C₁₅H₁₉NO 
• 1428479-68-8 5-[(3-{[4-(1H-tetrazol-1-yl)phenyl]acetyl}-3-azabicyclo[3.1.0]hex-6-yl)ethynyl]-2-benzofuran-1(3H)-one 
• 850808-43-4 tert-butyl 6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate 
• 893566-16-0 6-aminomethyl-3-azabicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester 
• 1428478-61-8 1-(6-ethynyl-3-azabicyclo[3.1.0]hex-3-yl)-2-[4-(1H-tetrazol-1-yl)phenyl]ethanone 
• 1428478-62-9 1-[6-(hydroxymethyl)-3-azabicyclo[3.1.0]hex-3-yl]-2-[4-(1H-tetrazol-1-yl)phenyl] ethanone 
• 850808-53-6 [3-(4-ethyl-benzyl)-3-aza-bicyclo[3.1.0]hex-6-yl]-methanol 

Relevant articles and documents

AMIDE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS

The present invention relates to compounds of formula (I), including their stereoisomers and pharmaceutically acceptable salts. This invention also relates to methods of making such compounds and pharmaceutical compositions comprising such compounds. The compounds of this invention are useful in the treatment of various disorders that are related to 5-hydroxytryptamine 4 (5-HT4) receptor.

5-AMINO-QUINOLINE-8-CARBOXAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS

The present invention relates to novel quinoline compounds of formula (I), and their pharmaceutically acceptable salts and process for their preparation. The compounds of formula (I) are useful in the treatment of various disorders that are related to 5-HT4 receptor agonists.