289043-10-3

Upstream product

• 3397-35-1 Z-L-leucine hydroxysuccinimide ester 
• 143745-54-4 N-(4-methoxy-phenyl)-ethylenediamine; hydrochloride 
• 20265-97-8 p-anisidine hydrochloride 
• 596120-09-1 (2-tert-butoxycarbonylamino-ethyl)-(4-methoxy-phenyl)-carbamic acid tert-butyl ester 
• 143745-54-4 N¹-(4-methoxyphenyl)ethane-1,2-diamine hydrochloride 

Downstream Products

• 596120-31-9 (S)-2-Amino-4-methyl-pentanoic acid [2-(4-methoxy-phenylamino)-ethyl]-amide 
• 289044-26-4 4-benzyloxy-N-{1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-benzamide 

Relevant academic research and scientific papers

Arylaminoethyl amides as inhibitors of the cysteine protease cathepsin K - Investigating P1′ substituents

Modeling, synthesis and in vitro activities of a series of arylaminoethyl amide based inhibitors of the cysteine protease cathepsin K are described.

Arylaminoethyl amides as novel non-covalent cathepsin K inhibitors

A series of Nα-benzyloxycarbonyl- and Nα-acyl-L-leucine(2-phenylaminoethyl)amide derivatives were prepared and evaluated for their inhibitory activity against rabbit and human cysteine proteases cathepsins K, L, and S. These data ind