28909-34-4 Usage
Uses
Used in Pharmaceutical Synthesis:
1,2-Benzisoxazole, 5-chloro-3-methylis used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and functional groups contribute to the development of new drugs with improved therapeutic properties.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1,2-Benzisoxazole, 5-chloro-3-methylis utilized for the design and development of novel drug candidates. Its presence in these compounds can enhance their pharmacological activity and selectivity, leading to more effective treatments for various diseases.
Used in Drug Development:
1,2-Benzisoxazole, 5-chloro-3-methylplays a significant role in drug development, where it is employed to create new chemical entities with potential therapeutic applications. Its unique structure allows for the exploration of new chemical space and the identification of promising drug candidates.
Used as a Research Tool:
In the study of biological molecules, 1,2-Benzisoxazole, 5-chloro-3-methylis used as a research tool to investigate the structures and functions of these molecules. Its incorporation into various chemical probes and ligands enables researchers to gain insights into the mechanisms of biological processes and the development of targeted therapies.
Used in Organic Synthesis:
1,2-Benzisoxazole, 5-chloro-3-methylis also used in organic synthesis for the preparation of other organic compounds. Its versatile structure and reactivity make it a valuable building block for the synthesis of complex organic molecules with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 28909-34-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,9,0 and 9 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 28909-34:
(7*2)+(6*8)+(5*9)+(4*0)+(3*9)+(2*3)+(1*4)=144
144 % 10 = 4
So 28909-34-4 is a valid CAS Registry Number.
28909-34-4Relevant academic research and scientific papers
Method for preparing benzisoxazole in one pot based on 2-hydroxyacetophenone oxime and derivatives thereof
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Paragraph 0020; 0024; 0025; 0026, (2017/08/24)
The invention relates to the technical field of medicinal chemistry and in particular discloses a method for preparing benzisoxazole in one pot based on 2-hydroxyacetophenone oxime and derivatives thereof. The preparation method is as follows: under microwave or oil bath heating conditions, in an organic solvent, one-pot inversion is carried out on 2-hydroxyacetophenone oxime and derivatives thereof to form benzisoxazole compounds by utilizing a fluorine-containing accelerator and alkali. The method for synthesizing benzisoxazole has the advantages that raw materials are rich in source and easy to get, synthetic steps are short, the operation is simple and convenient, the product yield is high, and the highest yield is 93%. A benzisoxazole structure exists in multiple drug molecules, so that the novel one-pot synthesis method disclosed by the invention has potential practical values.
Amino sulfonyl compound, preparation method and uses thereof
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Paragraph 0219; 0221, (2016/12/01)
The present invention relates to a new amino sulfonyl compound represented by a general formula I, or a tautomer, an enantiomer, a racemate or a pharmaceutically acceptable salt thereof, a preparation method, a pharmaceutical composition, and uses thereof, wherein the compound can be used for treatment of epilepsy, convulsion, obesity, and the like. The general formula I is defined in the specification.
Microwave induced synthesis of 3-substituted 1,2-benzisoxazole derivatives
Shastri,Pedgaokar,Selulkar,Jadhav
experimental part, p. 574 - 576 (2009/07/18)
A rapid, cost-effective and eco-friendly synthesis of 3-substituted 1,2-benzisoxazoles from o-hydroxy ketoximes in solvent free conditions using solid support under microwave irradiation has been achieved.
