2892-30-0

Basic information

• Product Name: 1-(3-bromo-2-hydroxy-5-methylphenyl)-1-propanone
• Synonyms: 1-(3-bromo-2-hydroxy-5-methylphenyl)-1-propanone
• CAS NO: 2892-30-0
• Molecular Weight: 243.1
• Mol File: 2892-30-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 133°C
• CAS DataBase Reference: 1-(3-bromo-2-hydroxy-5-methylphenyl)-1-propanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-bromo-2-hydroxy-5-methylphenyl)-1-propanone(2892-30-0)
• EPA Substance Registry System: 1-(3-bromo-2-hydroxy-5-methylphenyl)-1-propanone(2892-30-0)

Safety Data

• Hazardous Substances Data: 2892-30-0(Hazardous Substances Data)

Usage

Preparation

Preparation by bromination of 2-hydroxy-5-methylpropiophenone,with bromine,with N-bromosuccinimide in DMF, first at 0°, then at r.t. for 18 h (86%).

Upstream product

• 6627-55-0 2-bromo-p-cresol 
• 104-93-8 p-methylanizole 
• 938-45-4 2-propionyl-p-cresol 

Downstream Products

• 106942-92-1 2,6-bis(3-bromo-2-methoxy-5-methylphenyl)-3,5-dimethylpyrylium perchlorate 
• 106942-94-3 3,3'-(3,4,5-trimethyl-4H-pyran-2,6-diyl)bis(2-methoxy-5-methylbenzaldehyde) 
• 106942-95-4 3,3'-(3,4,5-trimethyl-4H-pyran-2,6-diyl)bis(2-methoxy-5-methylbenzenemethanol) 
• 106942-93-2 2,6-bis(3-bromo-2-methoxy-5-methylphenyl)-3,4,5-trimethyl-4H-pyran 
• 111999-77-0 25,26-dimethoxy-3,5,9,23-tetramethyl-4-(2-phenylethenyl)13,16,19-trioxa-27-oxoniatetracyclo<19.3.1.1.1>heptacosa-1(25),2,4,6(27),7,9,11(26),21,23-nonaene tetrafluoroborate 
• 111999-78-1 25,26-dimethoxy-3,5,9,23-tetramethyl-4-(2-phenylethenyl)13,16,19-trioxa-27-azatetracyclo<19.3.1.1.1>heptacosa-1(25),2,4,6(27),7,9,11(26),21,23-nonaene 
• 111999-81-6 25,26-dimethoxy-3,4,5,9,23,-pentamethyl-13,16,19-trioxa-27-phenyl-27-azoniatetracyclo<19.3.1.1.1>heptacosa-1(25),2,4,6(27),7,9,11(26),21,23-nonaene 
• 106942-90-9 1-(3-bromo-2-methoxy-5-methylphenyl)-1-propanone 

Relevant articles and documents

ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASES ASSOCIATED WITH P13K MODULATION

The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I), or a prodrug, solvate, enantiomer, st

4H-Pyran and Pyrylium Hemispherands: Partly Preorganized Ionophores with Reactive Molecular Cavities

The synthesis and reactivity of a 2,6-diaryl-substituted pyrylium cation incorporated in an 18-membered macrocycle (3a,b) has been studied.Hemispherands with a central pyridine (4a,b) and with alkyl- or phenyl-substituted pyridinium ions (5a,b) were obtai