289666-20-2Relevant academic research and scientific papers
Ring contraction through epoxide rearrangement: A formal synthesis of capsorubin
Constantino, Mauricio Gomes,Donate, Paulo Marcos,Frederico, Daniel,Carvalho, Tecia Vieira,Cardoso, Luiz Eduardo,Zukerman-Schpector, Julio
, p. 3327 - 3340 (2000)
An eight-step synthesis of the cyclopentane keto-alcohol 2, which has previously been converted in one step into the carotenoid pigment capsorubin (1), is described. The key step in our synthesis is a stereospecific epoxide rearrangement with ring contraction, thus producing the cyclopentane ring from an epoxide of a cyclohexene.
