289667-06-7

Upstream product

• 109-87-5 Dimethoxymethane 
• 168072-74-0 (S)-4-{(2R,4S,5R,6R)-6-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-hydroxy-ethyl]-5-hydroxy-4-methoxy-3,3-dimethyl-tetrahydro-pyran-2-ylmethyl}-[1,3]dioxolan-2-one 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 152998-13-5 (S)-1-((R)-2,2-Diethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-but-3-en-1-ol 
• 152998-14-6 (R)-2,2-Diethyl-4-((S)-1-methoxy-2,2-dimethyl-but-3-enyl)-[1,3]dioxolane 
• 168072-66-0 (S)-3-((R)-2,2-Diethyl-[1,3]dioxolan-4-yl)-3-methoxy-2,2-dimethyl-propionaldehyde 
• 168072-68-2 (2R,4S)-4-((R)-2,2-Diethyl-[1,3]dioxolan-4-yl)-4-methoxy-3,3-dimethyl-1-(S)-oxiranyl-butan-2-ol 
• 168072-69-3 (S)-4-[(2R,4S)-4-((R)-2,2-Diethyl-[1,3]dioxolan-4-yl)-2-hydroxy-4-methoxy-3,3-dimethyl-butyl]-[1,3]dioxolan-2-one 
• 168072-67-1 (1S,3R)-1-((R)-2,2-Diethyl-[1,3]dioxolan-4-yl)-1-methoxy-2,2-dimethyl-hex-5-en-3-ol 

Downstream Products

• 289667-08-9 {(4S,4aS,6R,8S,8aR)-6-[(S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-hydroxy-propyl]-8-methoxy-7,7-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-4-yl}-carbamic acid 2-trimethylsilanyl-ethyl ester 
• 168072-76-2 N-[(4S,4aS,6R,8S,8aR)-8-Methoxy-7,7-dimethyl-6-((S)-2-oxo-[1,3]dioxolan-4-ylmethyl)-hexahydro-pyrano[3,2-d][1,3]dioxin-4-yl]-benzamide 

Relevant academic research and scientific papers

A stereoselective synthesis of the C-10 to C-18 (right-half) fragment of mycalamides employing lewis acid promoted intermolecular aldol reaction.

[reaction: see text] Beginning with D-mannitol, a stereoselective synthesis of the right-half segment of the mycalamides has been accomplished by employing Lewis acid catalyzed intermolecular aldol reaction and oxypalladation as the key steps.

Diastereoselective synthesis of N-benzoyl mycalamine, the fully elaborated trioxadecalin nucleus of mycalamide. A. Control of the key N-acyl aminal stereocenter via carbamate acylation

A highly diastereoselective synthesis of N-benzoyl mycalamine (8), corresponding to the C(10)-C(18) amine fragment of mycalamide A, is described. The synthesis features a highly stereoselective acylation of carbamate 7 that permits the stereochemistry of