289686-88-0

Basic information

• Product Name: tert-butyl 4-[N-[7-chloro-2-hydroxymethyl-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate
• Synonyms: tert-butyl 4-[N-[7-chloro-2-hydroxymethyl-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate
• CAS NO: 289686-88-0
• Molecular Weight: 467.952
• Mol File: 289686-88-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-[N-[7-chloro-2-hydroxymethyl-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-[N-[7-chloro-2-hydroxymethyl-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate(289686-88-0)
• EPA Substance Registry System: tert-butyl 4-[N-[7-chloro-2-hydroxymethyl-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate(289686-88-0)

Safety Data

• Hazardous Substances Data: 289686-88-0(Hazardous Substances Data)

Upstream product

• 289686-86-8 2-acetoxymethyl-6-bromomethyl-7-chloro-3-methyl-3,4-dihydroquinazolin-4-one 
• 289686-85-7 2-acetoxymethyl-7-chloro-3,6-dimethyl-3,4-dihydroquinazolin-4-one 
• 289686-84-6 2-acetoxymethyl-7-chloro-6-methyl-3,4-dihydroquinazolin-4-one 
• 458533-73-8 2-methoxyacetamido-4-chloro-5-methyl N-methylbenzamide 
• 458533-71-6 methyl 2-methoxyacetamido-4-chloro-5-methylbenzoate 
• 289686-83-5 7-chloro-2-chloromethyl-6-methyl-3,4-dihydroquinazolin-4-one 
• 458533-75-0 2-methoxymethyl-7-chloro-3,6-dimethyl-3,4-dihydroquinazolin-4-one 
• 458533-77-2 2-hydroxymethyl-7-chloro-3,6-dimethyl-3,4-dihydroquinazolin-4-one 
• 458533-67-0 7-chloro-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 
• 458533-69-2 methyl 2-amino-4-chloro-5-methylbenzoate 
• 289686-80-2 2-cyano-5-chloro-4-methylaniline 
• 95-74-9 3-chloro-p-toluidine 
• 155184-81-9 2-amino-5-methyl-4-chlorobenzoic acid 
• 116010-06-1 N-(2-bromo-5-chloro-4-methylphenyl)acetamide 

Downstream Products

• 289686-89-1 tert-butyl 4-[N-[7-chloro-2-methanesulfonyloxymethyl-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate 
• 289686-91-5 tert-butyl4-[N-[2-diethylaminomethyl-7-chloro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate 
• 289686-93-7 tert-butyl 4-[N-[7-chloro-3-methyl-2-morpholinomethyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate 
• 289686-94-8 tert-butyl 4-[N-[7-chloro-3-methyl-2-pyrrolidinomethyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate 
• 289686-90-4 tert-butyl 4-[N-[7-chloro-3-methyl-2-(4-methylpiperazin-1-ylmethyl)-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate 
• 289686-92-6 tert-butyl 4-[N-[7-chloro-3-methyl-4-oxo-2-piperidin-1-ylmethyl-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate 
• 289686-97-1 tert-butyl 4-[N-[7-chloro-3-methyl-2-(4-(2-hydroxyethyl)piperazin-1-ylmethyl)-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate 
• 289686-98-2 tert-butyl 4-[N-[7-chloro-3-methyl-4-oxo-2-(4-phenylpiperazin-1-ylmethyl)-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate 

Relevant articles and documents

Anti-quinazoline compounds

Dihydroquinazoline derivatives of the formula where R3is —(CH2)p—A where p is from 1 to 4 and A is a 5- or 6-membered N-containing heterocyclic ring attached via the N atom or A is —NA′A″ wherein A′ and A″ are the same or different and are each a C1-C4alkyl group or their pharmaceutically acceptable salts possessing anti-cancer activity.