289703-22-6

Basic information

• Product Name: 10-deacetylbaccatin III 7,10-bis-trichloroacetate
• Synonyms: 10-deacetylbaccatin III 7,10-bis-trichloroacetate
• CAS NO: 289703-22-6
• Molecular Weight: 835.344
• Mol File: 289703-22-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 10-deacetylbaccatin III 7,10-bis-trichloroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 10-deacetylbaccatin III 7,10-bis-trichloroacetate(289703-22-6)
• EPA Substance Registry System: 10-deacetylbaccatin III 7,10-bis-trichloroacetate(289703-22-6)

Safety Data

• Hazardous Substances Data: 289703-22-6(Hazardous Substances Data)

Upstream product

• 32981-86-5 10-deacetylbaccatin III 
• 4124-31-6 trichloroacetic acid anhydride 
• 76-02-8 trifluoroacetyl chloride 

Downstream Products

• 1036915-57-7 C₅₄H₆₃Cl₆NO₁₈ 
• 881844-47-9 2-2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzensulfenyl)-4⁽⁵⁾-phenyl-5(R)-oxazolidine carboxylic acid 10-deacetyl-7,10-bis-trichloroacetylbaccatin III 13-yl-ester 
• 32981-86-5 10-deacetylbaccatin III 
• 397249-98-8 13-dehydro-10-deacetylbaccatin III 7,10-bis-trichloroacetate 

Relevant articles and documents

PROCESS FOR THE PURIFICATION 10-DEACETYBACCATINE III FROM 10-DEACETYL-2-DEBENZOYL-2-PENTENOYLBACCATINE III

A process for the preparation of 10-deacetyl-7,10-bis-trichloroacetylbaccatine III with HPLC purity higher than 99% and free from 2-debenzoyl-2-pentenoylbaccatine III by purification of 10-deacetyl-7,10-bis-trichloroacetylbaccatineIII followed by alkaline hydrolysis of the protecting groups in position 7 and 10.

SEMISYNTHESIS PROCESS FOR THE PREPARATION OF 10-DEACETYL-N-DEBENZOYL-PACLITAXEL

The invention relates to a process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel, a synthon useful for the preparation of taxanes with antitumour activity, and intermediates for the preparation thereof. The invention also discloses a process f

Process for the preparation of baccatin III derivatives

A process for the preparation of 14 beta-hydroxy-1,4-carbonate-deacetylbaccatin III and intermediates useful for the preparation of novel taxan derivatives with antitumor activity are disclosed.