289713-98-0Relevant academic research and scientific papers
Design and synthesis of a novel photoaffinity taxoid as a potential probe for the study of paclitaxel-microtubules interactions
Lin, Songnian,Fang, Kan,Hashimoto, Masaru,Nakanishi, Koji,Ojima, Iwao
, p. 4287 - 4290 (2000)
A novel and non-radioactive bifunctional photoaffinity probe (BPP) for the study of paclitaxel-microtubules interactions is designed and synthesized. This new BPP-taxoid bears a 3-nitro-5-trifluoromethyl- diazirinyl-phenoxyacetyl group at C-3'N for photoaffinity/photocleavage and a biotin subunit at C-7 for affinity chromatography. (C) 2000 Elsevier Science Ltd.
