289721-00-2

Upstream product

• 289720-99-6 (S,S)-(4-tert-butyl-4,5-dihydrooxazol-2-yl)-(4-tert-butyl-4,5-dihydrooxazol-2-yl)amine 
• 74-88-4 methyl iodide 
• 289720-98-5 2-amino-4,5-dihydro-(4S)-(1,1-dimethylethyl)-1,3-oxazole 
• 112245-13-3 (S)-tert-leucinol 

Relevant academic research and scientific papers

Siliceous mesocellular foam-supported aza(bisoxazoline)-copper catalysts

Aza(bisoxazoline) was easily immobilized on siliceous mesocellular foam (MCF) in a systematic approach. It was found that silanol precapping, linker group flexibility, ligand loading, and silanol postcapping were important factors to consider in optimizing silica-supported aza(bisoxazoline) catalysts. The optimized MCF-supported aza(bisoxazoline)-copper catalyst offered the same enantioselectivity as its homogeneous counterpart, and excellent recyclability. The heterogenized catalyst showed a much higher chemoselectivity in a short reaction time. The heterogenized aza(bisoxazoline)-copper(I) catalyst was successfully applied to a circulating flow-type packed bed reactor with excellent productivity and enantioselectivity. The circulating flow-type reactor was found to be very useful for gas-generating catalytic reactions such as cyclopropanation reaction.

Aza-bis(oxazolines): New chiral ligands for asymmetric catalysis

diagram presented Aza-bis(oxazolines) are introduced as chiral ligands for asymmetric catalysis combining the advantages of easy availability of bis(oxazolines) and backbone variability of aza-semicorrins. Especially, the title ligands could be attached t