289726-13-2

Upstream product

• 182212-07-3 α,β-O-allyl-D-mannopyranoside 
• 530-26-7 D-Mannose 
• 289726-12-1 allyl 6-O-trityl-D-mannopyranoside 
• 100-44-7 benzyl chloride 

Downstream Products

• 912651-02-6 2,3,4-tri-O-benzyl-D-mannono-1,5-lactone 

Relevant academic research and scientific papers

Synthesis of 1-deoxyhept-2-ulosyl-glycono-1,5-lactone utilizing α-selective O-glycosidation of 2,6-anhydro-1-deoxy-d-hept-1-enitols

A series of 1-deoxy-heptulo-2-pyranosyl-glycono-1,5-lactones were synthesized utilizing completely α-selective O-glycosidation of heptenitols. Anomeric configuration of the products was confirmed by 3JC,H coupling measurement and X-ray crystal structural analysis. The benzyl-protected ketosyl saccharides were partly unstable, and glycosidic linkage was prone to cleave under the usual debenzylation conditions. To prevent this, we surveyed various additives for the Pd-catalyzed hydrogenation reaction and found that basic alumina was the most effective.