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Ethanethioic acid, [[(phenylmethoxy)carbonyl]amino]-, S-phenyl ester, also known as phenylmethoxycarbonylaminoethanethioate or Z-Cysteine, is a chemical compound with the molecular formula C11H11NO3S. It is a derivative of ethanethioic acid, featuring a phenylmethoxycarbonyl group attached to the amino group and a phenyl group esterified to the sulfur atom. Ethanethioic acid, [[(phenylmethoxy)carbonyl]amino]-, S-phenyl ester is commonly used in organic synthesis, particularly in peptide chemistry, as a protecting group for cysteine residues during peptide synthesis. The phenylmethoxycarbonyl (Z) group can be selectively removed under mild conditions, allowing for the deprotection of the cysteine residue. Ethanethioic acid, [[(phenylmethoxy)carbonyl]amino]-, S-phenyl ester plays a crucial role in the synthesis of various biologically active peptides and proteins, as well as in the development of new drugs and pharmaceuticals.

2899-57-2

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2899-57-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2899-57-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,9 and 9 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2899-57:
(6*2)+(5*8)+(4*9)+(3*9)+(2*5)+(1*7)=132
132 % 10 = 2
So 2899-57-2 is a valid CAS Registry Number.

2899-57-2Relevant academic research and scientific papers

Synthesis of a 3-aminopiperidin-2,5-dione as a conformationally constrained surrogate of the Ala-Gly dipeptide

Estiarte, M.Angels,Diez, Anna,Rubiralta, Mario,Jackson, Richard F.W

, p. 157 - 161 (2007/10/03)

The preparation of the Boc-{Ala-Gly}-OBn pseudopeptide 4 is reported. The key intermediate, aminoester 5b, was obtained by a cross-coupling reaction of alaninezinc iodide 6 and the thioester of glycine 9.

A facile general synthesis of thiocarboxylate S-esters of glyphosphate and its derivatives

Mao,Franz

, p. 920 - 922 (2007/10/02)

Various glyphosate thiocarboxylate S-ester derivatives, e.g. S-alkyl 2-(phosphonomethylamino)ethanethioates and S-alkyl 2[(phenoxyphosphorylmethyl)amino]ethanethioates, are readily synthesized from N-benzyloxycarbonylglycine using N-methylene-tert-butylam

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