289909-60-0

Upstream product

• 474107-64-7 2,2-Dimethyl-propionic acid (E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-methyl-hex-2-enyl ester 
• 289909-50-8 (E)-(S)-6-(tert-Butyl-dimethyl-silanyloxy)-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-methyl-hex-2-en-1-ol 
• 289909-57-5 tert-Butyl-[(E)-(S)-4-ethyl-6-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-4-methyl-hex-5-enyloxy]-dimethyl-silane 
• 474115-82-7 (E)-(S)-4-Ethyl-6-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-4-methyl-hex-5-en-1-ol 
• 186581-53-3 diazomethane 

Relevant academic research and scientific papers

A novel method to generate chiral quaternary carbon centers of high enantiomeric purity using a highly stereoselective addition of vinylalanes to a chiral aldehyde

The anti addition of cyanocuprates to chiral pivalates 2 derived from aldehyde 1 generates aldehydes 3 with a chiral quaternary carbon center. The generation of the alcohol precursors was achieved by a highly stereoselective addition of vinylalanes on the aldehyde auxiliary. Piv = pivaloyl = 2,2- dimethylpropyl.