289909-70-2

Upstream product

• 931-48-6 2-cyclohexylacetylene 
• 75-24-1 trimethylaluminum 
• 80434-59-9 (1R,2S,5R)-2-isopropyl-5-methylcyclohexanecarboxaldehyde 

Relevant academic research and scientific papers

p-menthane-3-carboxaldehyde: A useful chiral auxiliary for the synthesis of chiral quaternary carbons of high enantiomeric purity

(+)- or (-)-p-Menthane-S-carboxaldehyde is made in two easy steps from (+)- or (-)-menthone, respectively. This auxiliary allows for the synthesis of carbonyl compounds bearing a α-chiral quaternary carbon. The flexibility, efficiency, and ease of use of

A novel method to generate chiral quaternary carbon centers of high enantiomeric purity using a highly stereoselective addition of vinylalanes to a chiral aldehyde

The anti addition of cyanocuprates to chiral pivalates 2 derived from aldehyde 1 generates aldehydes 3 with a chiral quaternary carbon center. The generation of the alcohol precursors was achieved by a highly stereoselective addition of vinylalanes on the aldehyde auxiliary. Piv = pivaloyl = 2,2- dimethylpropyl.