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Boc-Tyr(tBu)-Pro-OH is a chemical compound that features a Boc-protected tyrosine and a tert-butyl-protected proline, along with a carboxylic acid group. The Boc (tert-butoxycarbonyl) and tBu (tert-butyl) protective groups are integral to its structure, serving to temporarily shield reactive functional groups from unwanted reactions during peptide synthesis. Boc-Tyr(tBu)-Pro-OH is recognized for its role as a fundamental building block in the creation of peptides and small molecules within the field of organic chemistry. The Boc group's ease of removal under mild acidic conditions highlights its utility and popularity in peptide synthesis processes.

289910-65-2

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  • (2S)-1-[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoyl]pyrrolidine-2-carboxylic acid

    Cas No: 289910-65-2

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289910-65-2 Usage

Uses

Used in Organic Chemistry:
Boc-Tyr(tBu)-Pro-OH is used as a building block for the synthesis of peptides and small molecules, facilitating the construction of complex organic structures with precision and control over the reactive sites.
Used in Peptide Synthesis:
In the field of peptide synthesis, Boc-Tyr(tBu)-Pro-OH is utilized as a protected amino acid, allowing chemists to incorporate it into peptide chains with the assurance that the Boc group will protect the tyrosine's hydroxyl group from side reactions until it is ready to be deprotected.
Used in Pharmaceutical Development:
Boc-Tyr(tBu)-Pro-OH is employed in the development of pharmaceuticals, particularly in the synthesis of peptide-based drugs, where its protective groups ensure the stability and correct formation of the desired peptide sequences.
Used in Research and Development:
In research settings, Boc-Tyr(tBu)-Pro-OH is used as a component in the exploration of new chemical reactions and the synthesis of novel compounds, providing a controlled environment for studying the reactivity and properties of protected amino acids.

Check Digit Verification of cas no

The CAS Registry Mumber 289910-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,9,9,1 and 0 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 289910-65:
(8*2)+(7*8)+(6*9)+(5*9)+(4*1)+(3*0)+(2*6)+(1*5)=192
192 % 10 = 2
So 289910-65-2 is a valid CAS Registry Number.

289910-65-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-1-[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoyl]pyrrolidine-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names Boc-Tyr(tBu)-Pro-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:289910-65-2 SDS

289910-65-2Upstream product

289910-65-2Relevant articles and documents

β-Casomorphins: Substitution of phenylalanine with β-homo phenylalanine increases the μ-type opioid receptor affinity

Longobardo, Luigi,Melck, Dominique,Siciliano, Rosa,Santini, Antonello,Marzo, Vincenzo Di,Cammarota, Giancarlo

, p. 1185 - 1188 (2007/10/03)

Two analogues of bovine β-casomorphin-7 and β-casomorphin-5 containing a β-homo phenylalanine in substitution of the phenylalanine in position 3 were synthesised and tested for their μ-opioid receptor affinity. The modification enhanced the μ receptor affinity 5-fold in the case of modified β-CM-7 and 2-fold for modified β-CM-5 when compared to the natural peptides. (C) 2000 Elsevier Science Ltd. All rights reserved.

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