29001-25-0

Basic information

• Product Name: 6-amino-4,7-dimethyl-2H-chromen-2-one
• Synonyms: 2H-1-Benzopyran-2-one, 6-amino-4,7-dimethyl-; 6-Amino-4,7-dimethyl-2H-chromen-2-one; 6-Amino-4,7-dimethyl-chromen-2-one
• CAS NO: 29001-25-0
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.2105
• Mol File: 29001-25-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 397.1°C at 760 mmHg
• Flash Point: 231.2°C
• Density: 1.231g/cm³
• Vapor Pressure: 1.63E-06mmHg at 25°C
• Refractive Index: 1.613
• CAS DataBase Reference: 6-amino-4,7-dimethyl-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-amino-4,7-dimethyl-2H-chromen-2-one(29001-25-0)
• EPA Substance Registry System: 6-amino-4,7-dimethyl-2H-chromen-2-one(29001-25-0)

Safety Data

• Hazardous Substances Data: 29001-25-0(Hazardous Substances Data)

Upstream product

• 108-39-4 3-methyl-phenol 
• 14002-90-5 4,7-dimethyl-coumarin 
• 56024-16-9 4,7-dimethyl-6-nitro-coumarin 

Downstream Products

• 56110-93-1 4,9-dimethyl-1,2-diphenyl-3H-pyrano[3,2-e]indol-7-one 
• 401649-17-0 ethyl 2-[2-(4,7-dimethyl-2-oxo-2H-chromen-6-yl)hydrazino]phenylpropionate 
• 1246497-07-3 C₂₈H₂₁N₃O₆S 
• 1253853-74-5 C₁₈H₁₄N₂O₄ 
• 1253853-85-8 C₂₆H₁₈N₂O₄ 
• 1253853-80-3 C₂₆H₁₈N₂O₄ 
• 1318698-98-4 C₃₀H₂₅N₃O₅S 
• 1318698-93-9 C₂₈H₂₃N₃O₄ 
• 1318688-81-1 C₂₂H₁₇N₅O₅S 
• 1318688-78-6 C₂₄H₂₂N₄O₆ 
• 1318688-71-9 C₂₁H₁₈N₄O₄ 
• 1318688-68-4 C₂₁H₁₆ClN₃O₄ 
• 1318688-61-7 C₂₁H₁₅N₃O₆ 
• 1318688-54-8 C₂₃H₂₀N₂O₆ 

Relevant articles and documents

Design, synthesis, and antifungal evaluation of novel coumarin-pyrrole hybrids

A series of coumarin derivatives bearing a pyrrole scaffold were designed, prepared, and assessed for their in vitro antifungal activities against six phytopathogenic fungi. The antifungal activity screening results suggest that some synthesized hybrids exhibited potential fungicidal activities against the tested fungi. In particular, compounds 6j, 6k, 6o, 6p, and 6r displayed significant antifungal effects against Rhizoctorzia solani, and possessed EC50 values of 3.94, 7.75, 6.38, 6.25, and 7.67 μg/ mL, respectively. The above activities are more potent than the commercialized fungicide Boscalid (11.52 μg/mL) and Osthole (9.79 μg/mL). These results provide a significant reference for further rational design of coumarin-based fungicides.