290293-15-1Relevant articles and documents
Diastereoselective and enantioselective synthesis of 4'-aza analogues of 2',3'-dideoxynucleosides
Chiacchio, Ugo,Rescifina, Antonio,Corsaro, Antonio,Pistara, Venerando,Romeo, Giovanni,Romeo, Roberto
, p. 2045 - 2048 (2000)
A diastereo- and enantioselective synthesis of 4'-aza analogues of 2',3'-dideoxynucleosides has been designed by the strategy of the 1,3-dipolar cycloaddition reaction of a Vasella-type nitrone. The reaction leads to (1'R)- and (1'S)-4'-aza analogues of 2',3'-dideoxythimidine and fluorouridine, in enantiomerically pure forms. Copyright (C) 2000 Elsevier Science Ltd.