290293-17-3Relevant articles and documents
Enantioselective syntheses and cytotoxicity of N,O-nucleosides
Chiacchio, Ugo,Corsaro, Antonino,Iannazzo, Daniela,Piperno, Anna,Pistarà, Venerando,Rescifina, Antonio,Romeo, Roberto,Valveri, Vincenza,Mastino, Antonio,Romeo, Giovanni
, p. 3696 - 3702 (2007/10/03)
Enantiomers of 4′-aza-2′,3′-dideoxynucleosides have been prepared by two different synthetic approaches, on the basis of 1,3-dipolar cycloaddition of a chiral nitrone. Cytotoxicity and apoptotic activity have been investigated. (5′S)-5-Fluoro-1-isoxazolid