290293-17-3

Basic information

• Product Name: 1-{2-[6-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-isoxazolidin-5-yl}-5-methyl-1H-pyrimidine-2,4-dione
• CAS NO: 290293-17-3
• Molecular Weight: 607.779
• Mol File: 290293-17-3.mol

Chemical Properties

• CAS DataBase Reference: 1-{2-[6-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-isoxazolidin-5-yl}-5-methyl-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{2-[6-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-isoxazolidin-5-yl}-5-methyl-1H-pyrimidine-2,4-dione(290293-17-3)
• EPA Substance Registry System: 1-{2-[6-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-isoxazolidin-5-yl}-5-methyl-1H-pyrimidine-2,4-dione(290293-17-3)

Safety Data

• Hazardous Substances Data: 290293-17-3(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 20245-84-5 1-vinylthymine 

Relevant articles and documents

Enantioselective syntheses and cytotoxicity of N,O-nucleosides

Enantiomers of 4′-aza-2′,3′-dideoxynucleosides have been prepared by two different synthetic approaches, on the basis of 1,3-dipolar cycloaddition of a chiral nitrone. Cytotoxicity and apoptotic activity have been investigated. (5′S)-5-Fluoro-1-isoxazolid

Diastereoselective and enantioselective synthesis of 4'-aza analogues of 2',3'-dideoxynucleosides

A diastereo- and enantioselective synthesis of 4'-aza analogues of 2',3'-dideoxynucleosides has been designed by the strategy of the 1,3-dipolar cycloaddition reaction of a Vasella-type nitrone. The reaction leads to (1'R)- and (1'S)-4'-aza analogues of 2',3'-dideoxythimidine and fluorouridine, in enantiomerically pure forms. Copyright (C) 2000 Elsevier Science Ltd.