2903-46-0

Usage

Uses

Used in Herbicide Synthesis:
Ethyl 2-((2,6-diMethylphenyl)aMino)-2-oxoacetate is used as an intermediate in the synthesis of Metazachlor Oxalic Acid (M226230), a chloroacetanilide herbicide metabolite. This herbicide is effective in controlling a wide range of weeds, making it a valuable component in agricultural applications.
Used in Environmental Monitoring:
Ethyl 2-((2,6-diMethylphenyl)aMino)-2-oxoacetate is also used as a marker for the detection of Metazachlor Oxalic Acid in environmental samples. Its presence in surface water and groundwater can be indicative of urban surface runoff, which is essential for understanding the impact of herbicide use on the environment and developing strategies for mitigating potential harm.

Upstream product

• 4755-77-5 Ethyl oxalyl chloride 
• 87-62-7 2,6-dimethylaniline 
• 4058-04-2 N-phenyl-2,6-dimethylaniline 

Downstream Products

• 112547-79-2 ethyl 2-chloro-2-(2,6-dimethylphenylimino)acetate 
• 112547-83-8 ethyl 2-acetylhydrazono-2-(2,6-dimethylphenylamino)acetate 
• 64-17-5 ethanol 

Relevant academic research and scientific papers

Synthesis, crystal structures and magnetic properties of M IICuII chains (M=Mn and Co) with sterically hindered alkyl-substituted phenyloxamate bridging ligands

A series of neutral oxamato-bridged heterobimetallic chains of general formula [MCu(Lx)2(S)2]·p S·q H2O [p=0-1, q=0-2.5; L1=N-2,6-dimethylphenyloxamate, S=DMF with M=Mn (1 a) and Co (1 b); L2/su

Ligand design for heterobimetallic single-chain magnets: Synthesis, crystal structures, and magnetic properties of MIICuII (M = Mn, Co) chains with sterically hindered methyl-substituted phenyloxamate bridging ligands

Two new series of neutral oxamato-bridged heterobimetallic chains of general formula [MCu(Lx)2]· mDMSO (m = 0-4) (L 1 = N-2-methyl-phenyloxamate, M = Mn (1a) and Co (1b) ; L2 = N-2,6-dimethylphenyloxamate, M = M

Bis(oxamato)palladate(II) complexes: synthesis, crystal structure and application to catalytic Suzuki reaction

New bis(oxamato)palladate(II) complexes, [Pd(H2O)4][Pd(2,6-Me2pma)2]·2H2O (1), (n-Bu4N)2[Pd(2,6-Me2pma)2]·2H2O (2a), and (n-Bu4N)2[Pd(2,6-Me2pma)2]·2CHCl3 (2b) (2,6-Me2pma = N-2,6-dimethylphenyoxamate and n-Bu4N+ = tetra-n-butylammonium), have been synthesized and the structures of 1 and 2b characterized by single-crystal X-ray diffraction. Complex 1 is a double salt constituted by tetraaquapalladium(II) cations and bis(oxamato)palladate(II) anions interlinked by hydrogen bonds. The palladium(II) ions in 1 are four-coordinate with two oxygens and two nitrogens from two fully deprotonated oxamate ligands (anion), and four water molecules (cation) building centrosymmetric square-planar surroundings. Centrosymmetric bis(oxamato)palladate(II) anions occur in 2b as in 1, the charge balance in this compound being ensured by the bulky n-Bu4N+. The catalytic role of 1 and 2a for the Suzuki reaction has been investigated by using a series of aryl iodide/bromide derivatives in the conventional organic medium dimethylformamide. The tetraaquapalladium(II) unit in 1 appears to be active in the catalytic Suzuki cross-coupling reactions, but it readily decomposes to inactive palladium black.

Lanthanide complexes with N-(2,6-dimethylphenyl)oxamate: Synthesis, characterisation and cytotoxicity

The complexation reactions of Ce(III), Nd(III), Gd(III) and Er(III) ions with the chelating/ bridging monoanionic ligand N-(2,6-dimethylphenyl)oxamate (Hpma?) in basic media were performed in view of the potential applications of oxamate deriva

Copper-Catalyzed SN2′-Selective Allylic Substitution Reaction of gem-Diborylalkanes

A Cu/(NHC)-catalyzed SN2′-selective substitution reaction of allylic electrophiles with gem-diborylalkanes is reported. Different substituted gem-diborylalkanes and allylic electrophiles can be employed in this reaction, and various synthetic v

Copper-Catalyzed SN2′-Selective Allylic Substitution Reaction of gem-Diborylalkanes

A Cu/(NHC)-catalyzed SN2′-selective substitution reaction of allylic electrophiles with gem-diborylalkanes is reported. Different substituted gem-diborylalkanes and allylic electrophiles can be employed in this reaction, and various synthetic valuable functional groups can be tolerated. The asymmetric version of this reaction was initially researched with chiral N-heterocyclic carbene (NHC) ligands.

CuI/DMPAO-catalyzed N-arylation of acyclic secondary amines

DMPAO has been found to be a powerful ligand to enable copper-catalyzed coupling of aryl halides with aliphatic acyclic secondary amines take place under relatively mild conditions, and coupling of aryl halides with primary amines and cyclic secondary amines proceeds at low catalyst loading.

Copper-catalyzed 1,4-addition of organoboronates to alkylidene cyanoacetates: Mechanistic insight and application to asymmetric catalysis

In addition: A copper/N-heterocyclic carbene(NHC)-catalyzed 1,4-addition of organoboronates to alkylidene cyanoacetates was developed, in which the catalytic cycle is proposed to consist of a transmetalation/insertion/ligand exchange. An effective asymmetric variant has also been achieved by the use of a chiral NHC ligand (see scheme). Copyright

Copper-catalyzed asymmetric addition of arylboronates to isatins: A catalytic cycle involving alkoxocopper intermediates

A copper-catalyzed addition of arylboronates to isatins has been developed to give 3-aryl-3-hydroxy-2-oxindoles under mild conditions. The catalytic cycle of this process has been examined through a series of stoichiometric reactions and an effective asymmetric variant has also been described by the use of a chiral N-heterocyclic carbene ligand.

Triphenylphosphine-catalyzed simple synthesis of dimethyl 1-aryl-4-ethoxy-5-oxo-4,5-dihydro-1H-pyrrole-2,3-dicarboxylates

Ethyl 2-arylamino-2-oxo-acetates undergo a complex reaction with dimethyl acetylenedicarboxylate in the presence of triphenylphosphine to produce dimethyl 1-aryl-4-ethoxy-5-oxo-4,5-dihydro-1H-pyrrole-2,3-dicarboxylates in good yields. Dynamic NMR study of