29043-99-0Relevant academic research and scientific papers
α-Methylene-γ-butyrolactones with molluscicidal activity
Rucker,Hostettmann,Gajewski,Lobbert,Boken
, p. 941 - 945 (2007/10/02)
The α-methylene-γ-butyrolactones 1-28 were tested in vitro for molluscicidal activity against Biomphalaria glabrata. The racemic compound 25 shows the best activity. The synthesis was carried out by modified Reformatzky reaction of the corresponding carbo
Electrogenerated Zinc as the Catalyst in the Allylation of Carbonyl Compounds. Direct Synthesis of α-Methylene-γ-Lactones
Rollin, Y.,Derien, S.,Dunach, E.,Gebehenne, C.,Perichon, J.
, p. 7723 - 7732 (2007/10/02)
The electroreduction of a catalytic amount of ZnBr2 in acetonitrile provided a active Zn*, able to catalyze the reductive coupling of allyl bromides and chlorides with carbonyl compounds with high regioselectivity.Substituted α-methylene γ-lactones were o
Dimetalation of N-tert-Butylmethacrylamide: A New Synthetic Reagent
Fitt, John J.,Gschwend, Heinz W.
, p. 4257 - 4259 (2007/10/02)
Dimetalation of N-tert-butylmethacrylamide with n-butyllithium gives a reagent equivalent to the dianion of methacrylic acid.Its reaction with various electrophiles and the transformation of certain primary products to α-methylene lactones is exemplified.
Synthesis of α-Methylene-γ-butyrolactones: A Structure-Activity Relationship Study of Their Allergenic Power
Schlewer, Gilbert,Stampf, Jean-Luc,Benezra, Claude
, p. 1031 - 1038 (2007/10/02)
Thirty-five α-methylene-γ-butyrolactones has been prepared and their allergenic properties tested on the skin of guinea pigs experimentally sensitized to (a) alantolactone (1), (b) isoalantolactone (2), and (c) α-methylene-γ-butyrolactone (3).The two firs
