29069-22-5

Basic information

• Product Name: 11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl {4-[bis(2-chloroethyl)amino]phenyl}acetate
• CAS NO: 29069-22-5
• Molecular Formula: C₃₃H₄₁Cl₂NO₆
• Molecular Weight: 618.5877
• Mol File: 29069-22-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 767.8°C at 760 mmHg
• Flash Point: 418.1°C
• Density: 1.33g/cm³
• Vapor Pressure: 8.59E-25mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl {4-[bis(2-chloroethyl)amino]phenyl}acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl {4-[bis(2-chloroethyl)amino]phenyl}acetate(29069-22-5)
• EPA Substance Registry System: 11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl {4-[bis(2-chloroethyl)amino]phenyl}acetate(29069-22-5)

Safety Data

• Hazardous Substances Data: 29069-22-5(Hazardous Substances Data)

Usage

Chemical class

Synthetic corticosteroid and alkylating agent

Function

Used in the treatment of certain types of cancer, particularly leukemia and lymphoma

Mechanism of action

Combination of corticosteroid (reduces inflammation and suppresses immune system) and alkylating agent (interferes with cancer cell DNA, leading to destruction)

Administration

Often administered intravenously

Usage

Used in combination with other chemotherapy drugs to maximize effectiveness in killing cancer cells

Side effects

Can cause serious and potentially life-threatening side effects

Supervision

Should only be used under the direct supervision of a qualified healthcare professional

Chemical structure

Contains a steroid backbone with a phenyl acetate group attached, which has a bis(2-chloroethyl)amino substituent on the phenyl ring

Solubility

Likely soluble in organic solvents, such as ethanol or dimethyl sulfoxide (DMSO), due to its steroidal and phenyl acetate components

Stability

May be sensitive to light, heat, and moisture, as is common with steroidal compounds and chemotherapy drugs

Storage

Should be stored in a cool, dry place, protected from light, and in a sealed container to maintain stability

Purity

Typically synthesized and formulated with a high degree of purity to ensure effectiveness and minimize impurities that could cause adverse effects

Interactions

May interact with other medications, so it is important to inform healthcare providers of all medications being taken concurrently

Pregnancy and breastfeeding

Not recommended for use during pregnancy or breastfeeding due to potential harm to the fetus or nursing infant