1-(2-deoxy-3,5-di-O-p-toluyl-α-D-ribofuranosyl)-5-fluorouracil is a complex organic compound that serves as a modified nucleoside. It is characterized by the presence of a 5-fluorouracil (5-FU) base, which is a well-known antineoplastic and antimetabolite drug used in cancer chemotherapy. The compound features a 2-deoxy-D-ribose sugar moiety, which is essential for its interaction with cellular enzymes and incorporation into RNA. The 3,5-di-O-p-toluyl protecting groups are added to the ribose sugar to enhance the stability and solubility of the compound, making it more suitable for pharmaceutical applications. This chemical structure plays a crucial role in the compound's ability to inhibit thymidylate synthase, a key enzyme in DNA synthesis, thereby disrupting the proliferation of cancer cells.
2907-25-7
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Basic information
- Product Name: 1-(2-deoxy-3,5-di-O-p-toluyl-α-D-ribofuranosyl)-5-fluorouracil
- Synonyms:
- CAS NO:2907-25-7
- Molecular Formula:
- Molecular Weight: 482.465
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1-(2-deoxy-3,5-di-O-p-toluyl-α-D-ribofuranosyl)-5-fluorouracil(CAS DataBase Reference)
- NIST Chemistry Reference: 1-(2-deoxy-3,5-di-O-p-toluyl-α-D-ribofuranosyl)-5-fluorouracil(2907-25-7)
- EPA Substance Registry System: 1-(2-deoxy-3,5-di-O-p-toluyl-α-D-ribofuranosyl)-5-fluorouracil(2907-25-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 2907-25-7(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 2907-25-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,0 and 7 respectively; the second part has 2 digits, 2 and 5 respectively.Calculate Digit Verification of CAS Registry Number 2907-25:
(6*2)+(5*9)+(4*0)+(3*7)+(2*2)+(1*5)=87
87 % 10 = 7
So 2907-25-7 is a valid CAS Registry Number.
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1-(2-deoxy-3,5-di-O-p-toluyl-α-D-ribofuranosyl)-5-fluorouracil
