2907-52-0Relevant academic research and scientific papers
New strategy for production of primary alcohols from aliphatic olefins by tandem cross-metathesis/hydrogenation
Jia, Ruilong,Zuo, Zhijun,Li, Xu,Liu, Lei,Dong, Jinxiang
supporting information, p. 1525 - 1529 (2019/11/11)
Primary alcohols are widely used in industry as solvents and precursors of detergents. The classic methods for hydration of terminal alkenes always produce the Markovnikov products. Herein, we reported a reliable approach to produce primary alcohols from terminal alkenes combining with biomass-derived allyl alcohol by tandem cross-metathesis/hydrogenation. A series of primary alcohol with different chain lengths was successfully produced in high yields (ca. 90percent). Computational studies revealed that self-metathesis and hydrogenation of substrates are accessible but much slower than cross-metathesis. This new methodology represents a unique alternative to primary alcohols from terminal alkenes.
Enantiospecific total synthesis of the squalene synthase inhibitors (-)-CJ-13,982 and its enantiomer from a common intermediate
Sturgess, Dayna,Chen, Zongjia,White, Jonathan M.,Rizzacasa, Mark A.
, p. 234 - 239 (2018/03/21)
The total syntheses of both the natural and unnatural enantiomers of the alkyl citrate natural product CJ-13,982 (1) from the common d-ribose-derived acid 6 are described.
REGIOSPECIFIC RING OPENING OF α,β-EPOXYSILANES WITH SILICON TETRAFLUORIDE AND APPLICATION TO THE SYNTHESIS OF FLUOROALKENES
Shimizu, Makoto,Yoshioka, Hirosuke
, p. 967 - 970 (2007/10/02)
α,β-Epoxysilanes undergo the ring opening-fluorination with silicon tetrafluoride in the presence of diisopropylethylamine and water to give β-fluoro-β-silyl alcohols specifically, and the subsequent olefination with potassium hexamethyldisilazide affords fluoroalkenes in good yield.
