290817-84-4

Usage

InChI:InChI=1/C10H18N2/c1-2-8-7-12-4-3-9(8)5-10(12)6-11/h2,8-10H,1,3-7,11H2/t8-,9-,10-/m0/s1

Downstream Products

• 849025-11-2 1-{3,5-bis(trifluoromethyl)phenyl}-3-{(2S,5R)-5-vinyl-1-azabicyclo[2.2.2]oct-2-ylmethyl}thiourea 
• 849025-09-8 1-{3,5-bis(trifluoromethyl)phenyl}-3-{(2S,5R)-5-vinyl-1-azabicyclo[2.2.2]oct-2-ylmethyl}urea 
• 634180-59-9 (1S,2S,4S,5R)-2-(N-(isopropyl)aminomethyl)-5-ethyl-1-azabicyclo[2.2.2]octane 

Relevant academic research and scientific papers

Unusual stabilization of 1,2-diamino derivatives of quincorine and quincoridine by carbon dioxide: Persistent crystalline prim-ammonium-carbamate salts and their reactivity towards isatoic acid anhydride

The reaction of N-methylisatoic anhydride 1 with a series of quincorine (QCI) and quincoridine (QCD) derivatives furnished the corresponding QCI- and QCD-substituted anthranilic acid amides 4-9. In the synthesis of 4-9, we investigated the influence of th

Recalcitrant S(N)2 displacements at carbon C9 of quincorine and quincoridine: 1,2-Amino halides and mesylates with configurationally rigid nitrogen

S(N)2 reactions at carbon C9 of Quincorine (QCI) and Quincoridine (QCD) were investigated and found to be difficult, due to the special structural ('β-amino effect') and conformational factors. Efficient experimental procedures for displacement with a variety of carbon and heteroatom nucleophiles were developed. (C) 2000 Elsevier Science Ltd.