29084-13-7Relevant academic research and scientific papers
VINYL SULPHONES DERIVED FROM THIOGLYCOSIDES: SYNTHESIS AND ALKYLATION
Cassidy, Joseph F.,Williams, J. Michael
, p. 4355 - 4358 (2007/10/02)
Vinyl sulphones (1-sulfonyl glycals) are formed in good yield by elimination of propanone from 2,3-O-isopropylidene derivatives of D-mannopyranosyl and L-rhamnopyranosyl sulphones.Attempted conjugate addition of carbon nucleophiles to these vinyl sulphones, which are deactivated towards nucleophiles by the ring oxygen atom, was unsuccessful but lithiation followed by methylation yielded the 2-methyl vinyl sulphone derivatives when t-butyl sulphones rather than phenyl sulphones were used.
