29126-11-2

Usage

Uses

Used in Pharmaceutical Industry:
(6R,7R)-3-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester is used as a building block for the synthesis of various pharmaceutical compounds due to its complex molecular structure and the presence of multiple functional groups.
Used in Chemical Industry:
In the chemical industry, (6R,7R)-3-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester is used as an intermediate in the production of other complex organic molecules, taking advantage of its unique structural features and reactivity.

Upstream product

• 15681-48-8 lithium dimethylcuprate 
• 123054-37-5 (6R,7R)-3-(1-Methyl-1H-tetrazol-5-ylsulfanyl)-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 123054-30-8 (7R)-7-[(phenylacetyl)amino]-3-trifluoromethanesulfonyloxy-3-cephem-4-carboxylate, 4-methoxybenzyl ester 
• 104146-10-3 (6R,7R)-3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 101156-40-5 (6R,7R)-4-methoxybenzyl-3-(iodomethyl)-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 107447-98-3 (6R,7R)-4-methoxybenzyl 3-(acetoxymethyl)-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 101156-43-8 4-methoxybenzyl 7β-phenylacetamido-3-methylenecepham-4-carboxylate 
• 994-89-8 tributylethynyltin 
• 104146-10-3 (6R,7R)-3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 

Relevant academic research and scientific papers

A facile synthesis of 7-amino-3-desacetoxycephalosporanic acid derivatives by indium-mediated reduction of 3-iodomethylcephems in aqueous media

An efficient reductive conversion of 3-iodomethylcephalosporin and 3- acetoxymethylcephalosporin derivatives mediated by indium into the corresponding 3-methylcephems and 3-methylenecephams in moderate to good yields has been developed in an aqueous system. 3-Methylenecephams are converted into the corresponding 3-methylcephems under previously reported basic conditions quantitatively. (C) 2000 Elsevier Science Ltd.

Samarium Diiodide Mediated Reduction of Allyl Halides. A New Reductive Approach to Exomethylene Cephams.

A new method for the synthesis of exomethylene cepham based on the use of samarium diiodide is described.The reaction proved to be chemo-, regio-, and stereo-selective affording the exomethylene cephams possessing the natural configuration at C-4 in high

Palladium Catalysis in Cephalosporin Chemistry: General Methodology for the Synthesis of Cephem Side Chains

We describe in full the palladium-catalyzed coupling of 3-(triflyloxy)cephems with organotin compounds, leading to the synthesis of 3-alkenyl-, 3-alkynyl-, and 3-arylcephems under exceptionally mild conditions.While this approach was not satisfactory for

Reactions of organocuprates with vinyl-triflates and related cephems: A novel approach to 3-substituted cephalosporins

Vinyl-triflates and related 3-substituted cephems readily undergo addition-elimination reactions with a variety of organocuprates to form new carbon-carbon bonds. This chemistry presents a novel approach to the synthesis of 3-alkyl, 3-aryl, and 3-alkenylcephalosporins.