291289-50-4 Usage
Uses
Used in Pharmaceutical Research and Development:
4-(2,4-Difluoro-phenyl)-piperidine is utilized as a key intermediate in the synthesis of various drugs and biologically active molecules, contributing to the development of novel therapeutic agents.
Used in the Synthesis of Neurological Disorder Treatments:
In the field of neurology, 4-(2,4-Difluoro-phenyl)-piperidine is employed as a building block for the creation of potential treatments targeting neurological disorders, capitalizing on its structural and pharmacological properties to modulate neurological functions.
Used in Anti-Inflammatory Drug Development:
4-(2,4-Difluoro-phenyl)-piperidine is harnessed as a component in the design of anti-inflammatory drugs, leveraging its chemical properties to combat inflammation and associated conditions.
Used in Cancer Therapy:
4-(2,4-Difluoro-phenyl)-piperidine is applied in the development of cancer therapeutics, where its incorporation into drug molecules can potentially enhance their efficacy in treating cancer.
Used in Medicinal Chemistry:
In the domain of medicinal chemistry, 4-(2,4-Difluoro-phenyl)-piperidine is utilized as a crucial compound for the exploration and advancement of new drug candidates, underpinning the discovery of innovative pharmaceuticals with improved therapeutic profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 291289-50-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,1,2,8 and 9 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 291289-50:
(8*2)+(7*9)+(6*1)+(5*2)+(4*8)+(3*9)+(2*5)+(1*0)=164
164 % 10 = 4
So 291289-50-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H13F2N/c12-9-1-2-10(11(13)7-9)8-3-5-14-6-4-8/h1-2,7-8,14H,3-6H2
291289-50-4Relevant academic research and scientific papers
DRUG COMBINATIONS CONTAINING PDE4 INHIBITORS AND NSAIDS
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, (2012/02/15)
The present invention relates to new drug combinations which contain in addition to one or more PDE4-inhibitors at least one NSAID (=non-steroidal anti-inflammatory drug) (2), processes for preparing them and their use in treating in particular respiratory complaints such as for example COPD, chronic sinusitis and asthma. The invention particularly relates to those drug combinations which contain, in addition to one or more, preferably one PDE4 inhibitor of general formula 1 wherein X is SO or SO2, but preferably SO, and wherein R1, R2, R3 and R4 have the meanings given in claim 1, at least one NSAID (2), the preparation thereof and the use thereof for the treatment of respiratory complaints.
DISUBSTITUTED PHENYLPIPERIDINES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION
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Page/Page column 24-25, (2010/11/27)
The present invention relates to compounds of the formulae (4), (5) or (6), and their use in the treatment of central nervous system disorders.
Tricyclic benzimidazoles and their use as metabotropic glutamate receptor modulators
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Page/Page column 45, (2008/06/13)
The invention provides for a compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein R1, R2, R3, A, B, D, m, n, x, and y are defined as described in the specification. The invention additionally provides a pharmaceutically composition comprising the compound of formula I, together with a method of using the same to treat or prevent neurological and psychiatric disorders. The compounds are useful in therapy related to the treatment or prevention of mGluR2 receptor-mediated disorders.
