291297-63-7Relevant academic research and scientific papers
Structural determination of sulfoquinovosyldiacylglycerol by chiral syntheses
Hanashima, Shinya,Mizushina, Yoshiyuki,Yamazaki, Takayuki,Ohta, Keisuke,Takahashi, Shunya,Koshino, Hiroyuki,Sahara, Hiroeki,Sakaguchi, Kengo,Sugawara, Fumio
, p. 4403 - 4407 (2000)
Chiral sulfoquinovosyldiacylglycerols (SQDGs) have been synthesized to determine the absolute stereochemistry and the biological activities. The 1 H NMR spectrum of a natural SQDG is comparable to that of synthetic (2S)-SQDG rather than that of the (2R) analogue. The biological activity of the respective isomers for DNA polymerase α and β inhibition was not distinguishable in the enzymatic assay.
