291304-35-3

Upstream product

• 439264-95-6 (2S,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-2-(3-hydroxy-propyl)-tetrahydro-pyran-3-ol 
• 439264-93-4 3-((5S,6R)-5-Benzyloxy-6-benzyloxymethyl-5,6-dihydro-4H-pyran-2-yl)-propionic acid methyl ester 
• 177328-07-3 Trifluoro-methanesulfonic acid (5S,6R)-5-benzyloxy-6-benzyloxymethyl-5,6-dihydro-4H-pyran-2-yl ester 
• 796128-15-9 (2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-prop-2-ynyl-3-acetoxytetrahydropyran 

Downstream Products

• 796128-20-6 (4aS,6R,7S,8aR)-7-Benzyloxy-6-benzyloxymethyl-2-trimethylsilanylethynyl-octahydro-pyrano[3,2-b]pyran-2-ol 

Relevant academic research and scientific papers

A flexible approach toward trans-fused polycyclic tetrahydropyrans. A synthesis of prymnesin and yessotoxin units

(Chemical Equation Presented) Ru-catalyzed cycloisomerization and oxidative cyclization of bis-homopropargylic alcohols provide a rapid iterative approach to structural units of the ladder toxins.

Concise synthesis of cyclic ethers via the palladium-catalyzed coupling of ketene acetal triflates and organozinc reagents. Application to the iterative synthesis of polycyclic ethers

The reaction of the ketene acetal triflates 9a-e and a zinc homoenolate 10 in the presence of a catalytic amount of Pd(PPh3)4 gave the enol ethers 11a-e in good yields. The products were converted to the corresponding cyclic ethers 1