29134-16-5

Upstream product

• 105746-14-3 1-(n-pentyl)-4-phenylpiperazine 
• 32779-37-6 2,5-dibromopyrimidine 
• 98-80-6 phenylboronic acid 
• 22536-67-0 2,5-dichloropyrimidine 
• 32779-36-5 5-Bromo-2-chloropyrimidine 
• 657408-07-6 dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane 
• 1670-14-0 benzamidine monohydrochloride 
• 7089-34-1 ((Z)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate 
• 34713-70-7 2-Phenylpropanal 
• 109507-03-1 N,N,N',N'-tetramethyl-2-phenyl malondialdehyde diimine hydrochloride 
• 100-47-0 benzonitrile 
• 99939-04-5 4-Phenyl-1H-pyrazol-1-amin 
• 106636-96-8 5-phenyl-1,2,3-triazine 
• 825-60-5 benzimidic acid ethyl ester 

Downstream Products

• 1200124-05-5 2-(2-chlorophenyl)-5-phenylpyrimidine 
• 1242673-27-3 2-(5-phenylpyrimidin-2-yl)phenyl acetate 
• 1217189-25-7 2-(2,6-dichlorophenyl)-5-phenylpyrimidine 

Relevant academic research and scientific papers

Synthesis of novel Schiff bases as stable enol-imine-containing diazene bonds and pyrimidines using trimethinium salts

Novel derivatives of Schiff bases with diazene bonds and six new 2,5-disubstituted pyrimidine derivatives were synthesized by reaction of 2-substituted trimethinium salts with 4-aminoazobenzene or benzamidine hydrochloride, respectively, by a simple method and using inexpensive reagents. The purity and molecular structure of the new compounds were determined by elemental analysis, mass spectrometry, infrared, ultraviolet/visible, as well as proton nuclear magnetic resonance (1H NMR) and carbon-13 nuclear magnetic resonance (13C NMR) spectroscopy.

Iron Catalysis for Modular Pyrimidine Synthesis through β-Ammoniation/Cyclization of Saturated Carbonyl Compounds with Amidines

An efficient method for the modular synthesis of various pyrimidine derivatives by means of the reactions of ketones, aldehydes, or esters with amidines in the presence of an in situ prepared recyclable iron(II)-complex was developed. This operationally simple reaction proceeded with broad functional group tolerance in a regioselective manner via a remarkable unactivated β-C-H bond functionalization. Control experiments were performed to gain deep understanding of the mechanism, and the reactions are likely to proceed through a designed TEMPO complexation/enamine addition/transient α-occupation/β-TEMPO elimination/cyclization sequence.

ORGANOMETALLIC IRIDIUM COMPLEX, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE

PROBLEM TO BE SOLVED: To provide a long-lifetime organometallic iridium complex exhibiting yellow light emission with high emission efficiency as a novel substance. SOLUTION: The organometallic iridium complex includes a ligand in which an unsubstituted phenyl group is bonded to each of the 2-position and the 5-position of pyrimidine. The organometallic iridium complex has a structure represented by General Formula (G1). COPYRIGHT: (C)2016,JPO&INPIT

A arylpyrimidines and its derivatives preparation method (by machine translation)

This invention has offered a kind of arylpyrimidines and process for preparing derivatives thereof, comprising the following steps: S1) shown in the formula (II) 2 the iminium salts dial two substituted propionic [...], shown in formula (III) compound with a nitrile group of alkaline catalyst 1st reaction in the organic solvent, get mixed solution; S2) in the mixed solution is added with ammonium salt and 2nd alkaline catalyst, for the reaction, formula (I) shown in the arylpyrimidines and its derivatives. Compared with the prior art, this invention is in the presence of the alkaline catalyst, 2 the iminium salts dial two substituted propionic [...], of nitrile compounds and ammonium salt [3+2 + 1] ternary cyclization reaction to construct a pyrimidine ring, in order to get arylpyrimidines and its derivatives, this method does not use the noble metal catalyst, line is simple, low cost, high controllability of the process, easy industrialization, reduces the waste of relatively high yield and emissions. (by machine translation)

Organometallic Iridium Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device

To provide a long-lifetime organometallic iridium complex exhibiting yellow light emission with high emission efficiency as a novel substance. The organometallic iridium complex includes a ligand in which an unsubstituted phenyl group is bonded to each of

Ruthenium-catalyzed double-fold C-H tertiary alkoxycarbonylation of arenes using di-tert-butyl dicarbonate

An efficient ruthenium-catalyzed double-fold C-H alkoxycarbonylation of arenes was developed using di-tert-butyl dicarbonate as the tertiary esterification reagent, which leads to a direct route to valuable 2,6-dicarboxylated products. This journal is

Inverse electron demand diels-alder reactions of 1,2,3-triazines: Pronounced substituent effects on reactivity and cycloaddition scope

A systematic study of the inverse electron demand Diels-Alder reactions of 1,2,3-triazines is disclosed, including an examination of the impact of a C5 substituent. Such substituents were found to exhibit a remarkable impact on the cycloaddition reactivity of the 1,2,3-triazine without altering, and perhaps even enhancing, the intrinsic cycloaddition regioselectivity. The study revealed not only that the reactivity may be predictably modulated by a C5 substituent (R = CO2Me > Ph > H) but also that the impact is of a magnitude to convert 1,2,3-triazine (1) and its modest cycloaddition scope into a heterocyclic azadiene system with a reaction scope that portends extensive synthetic utility, expanding the range of participating dienophiles. Significantly, the studies define a now powerful additional heterocyclic azadiene, complementary to the isomeric 1,2,4-triazines and 1,3,5-triazines, capable of dependable participation in inverse electron demand Diels-Alder reactions, extending the number of complementary heterocyclic ring systems accessible with implementation of the methodology.

Palladium-Catalyzed Regioselective C-H Bond ortho-Acetoxylation of Arylpyrimidines

An efficient and regioselective palladium-catalyzed ortho C-H acetoxylation reaction was developed to afford, ortho monoacetoxylated arylpyrimidmes in good to excellent yields by using cupric trifluoroacetate as a cocatalyst. A wide variety of oxygenated

Titanium catalyzed one-pot multicomponent coupling reactions for direct access to substituted pyrimidines

A titanium-catalyzed 3-component coupling reaction can be used to generate tautomers of 1,3-diimines. These diimines produced in situ undergo condensation with amidines in a one-pot procedure to provide substituted pyrimidines. Seventeen examples of pyrimidines are provided using this one-pot, 4-component procedure from simple starting materials. In some cases, catalyst architecture can be tuned to control the regioselectivity of the alkyne addition. Finally, the regioselectivity of amidine addition to unsymmetrical 1,3-diimines is discussed.

Palladium-catalyzed monoselective halogenation of C-H bonds: Efficient access to halogenated arylpyrimidines using calcium halides

A wide variety of ortho-halogenated arylpyrimidines were prepared with high monoselectivity and functional-group tolerance by using calcium halides as crucial halogenating agents and cupric trifluoroacetate as oxidant in the presence of air.