291520-65-5Relevant academic research and scientific papers
Synthetic studies on the sarcodictyins: Synthesis of fully functionalized cyclization precursors
Ceccarelli, Simona M,Piarulli, Umberto,Gennari, Cesare
, p. 8531 - 8542 (2007/10/03)
A strategy featuring a key retrosynthetic disconnection at the C2-C3 position was applied to the total synthesis of the common diterpenoid tricyclic skeleton of sarcodictyins and eleutherobin. Fully functionalized cyclization precursors were accessed via a brief and convergent route, making use of unprecedented synthetic transformations.
Studies on the stereoselective synthesis of the marine antitumor agent eleutherobin
Carter, Rich,Hodgetts, Kevin,McKenna, Jeff,Magnus, Philip,Wren, Stephen
, p. 4367 - 4382 (2007/10/03)
(+)-Carvone has been converted into the sulfone 14 which comprises the left-hand side of the cytotoxic sesquiterpene, eleutherobin 1. Julia coupling of 14 to the aldehyde 21, followed by oxidation, dissolving metal reduction and stereoselective reduction
