291534-13-9

Basic information

• Product Name: methyl 2-{[4'-methoxy(1,1'-biphenyl)-4-yl]sulfonyl}amino-6-(4N-acetylpiperazin-1N-yl)hex-4-ynoate
• Synonyms: methyl 2-{[4'-methoxy(1,1'-biphenyl)-4-yl]sulfonyl}amino-6-(4N-acetylpiperazin-1N-yl)hex-4-ynoate
• CAS NO: 291534-13-9
• Molecular Weight: 513.615
• Mol File: 291534-13-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-{[4'-methoxy(1,1'-biphenyl)-4-yl]sulfonyl}amino-6-(4N-acetylpiperazin-1N-yl)hex-4-ynoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-{[4'-methoxy(1,1'-biphenyl)-4-yl]sulfonyl}amino-6-(4N-acetylpiperazin-1N-yl)hex-4-ynoate(291534-13-9)
• EPA Substance Registry System: methyl 2-{[4'-methoxy(1,1'-biphenyl)-4-yl]sulfonyl}amino-6-(4N-acetylpiperazin-1N-yl)hex-4-ynoate(291534-13-9)

Safety Data

• Hazardous Substances Data: 291534-13-9(Hazardous Substances Data)

Upstream product

• 291534-11-7 methyl 2-{[4'-methoxy(1,1'-biphenyl)-4-yl]sulfonyl}amino-6-[4N-(tert-butoxycarbonyl)piperazin-1N-yl]hex-4-ynoate 
• 291534-09-3 methyl 2-{[4'-methoxy(1,1'-biphenyl)-4-yl]sulfonyl}aminopent-4-ynoate 
• 50428-03-0 D,L-propargylglycine 
• 108-24-7 acetic anhydride 
• 70837-20-6 propargyclycine methyl ester hydrochloride 

Relevant articles and documents

Development of new carboxylic acid-based MMP inhibitors derived from functionalized propargylglycines

A series of carboxylic acids were prepared from a propargylglycine scaffold and tested for efficacy as matrix metalloproteinase (MMP) inhibitors. Detailed SAR for the series is reported for four enzymes within the MMP family. The inhibitors were typically