29169-13-9Relevant academic research and scientific papers
Mild air-oxidation of 1,3-dicarbonyl compounds with cesium salts: Novel α-hydroxylation accompanied by partial hydrolysis of malonate derivatives
Watanabe, Toshiko,Ishikawa, Tsutomu
, p. 7795 - 7798 (2007/10/03)
1,3-Dicarbonyl compounds (1) were efficiently oxygenated at the α-position with cesium salts, such as CsF or Cs2CO3 (0.1 Meq) in DMF at room temperature. Reaction of malonate derivatives (1a, b) with excess amount (2 Meq) of Cs2
Oxidation of 1,3-dicarbonyl compounds using (camphorylsulfonyl)oxaziridines
Davis, Franklin A.,Liu, Hu,Chen, Bang-Chi,Zhou, Ping
, p. 10481 - 10492 (2007/10/03)
The oxidation of 1,3-dicarbonyl compounds with (camphorylsulfonyl)oxaziridines 2 was studied in both cyclic and acyclic systems. Two reaction pathways were identified: Enolate α-hydroxylation and a novel Baeyer-Villiger type oxidation. The Baeyer-Villiger oxidation product was observed only for the ketones and arises via rearrangement of an alkoxy epoxide. Synthetically useful ee's (82-95%) were observed only for enolates of β-ketoesters where the keto group is part of a 6-membered ring.
Oxidation of α-acetoxy acetals with trichloroisocyanuric acid
Benincasa,Grandi,Ghelfi,Pagnoni
, p. 3463 - 3470 (2007/10/03)
α-Acetoxy acid methyl esters are prepared in excellent yields by treating aliphatic α-acetoxy dimethyl acetals with trichloroisocyanuric acid in DMF.
