29169-64-0 Usage
Description
(R)-(-)-O-Formylmandeloyl chloride is a colorless to light yellow liquid with specific chemical properties that make it suitable for various applications in different industries. It is a chiral compound, which means it has a non-superimposable mirror image, and this characteristic plays a crucial role in its uses.
Uses
Used in Pharmaceutical Industry:
(R)-(-)-O-Formylmandeloyl chloride is used as a chiral resolving agent for the resolution of spirobiindane. This application is significant because the ability to separate chiral compounds is essential in the development of pharmaceuticals, as the different enantiomers of a drug can have different biological activities and effects.
Used in Chemical Synthesis:
(R)-(-)-O-Formylmandeloyl chloride can also be used as an intermediate in the synthesis of various organic compounds. Its unique structure allows it to be a valuable building block for creating complex molecules with specific properties and functions.
Used in Research and Development:
In the field of research and development, (R)-(-)-O-Formylmandeloyl chloride serves as a valuable compound for studying the properties and behavior of chiral molecules. This knowledge can be applied to develop new drugs, materials, and technologies that rely on the unique properties of chiral compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 29169-64-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,1,6 and 9 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 29169-64:
(7*2)+(6*9)+(5*1)+(4*6)+(3*9)+(2*6)+(1*4)=140
140 % 10 = 0
So 29169-64-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H7ClO3/c10-9(12)8(13-6-11)7-4-2-1-3-5-7/h1-6,8H/t8-/m1/s1
29169-64-0Relevant articles and documents
Preparation method D - (-) - formyl mandelic acid chloride
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Paragraph 0038-0041, (2021/09/08)
D - Mandelic acid is used. Dichloromethane is reacted with little excess of anhydrous formic acid under the catalysis of activated carbon, and a formylation reaction takes place with solid light as a dehydrating agent to obtain a colorless viscous D (-) formyl mandelic acid which is used directly in the next step without purification. The colorless viscous material D (-) formyl mandelic acid is added with dichloromethane, the activated carbon catalyst is added, the light solution is added dropwise, the heat insulation reaction is finished, and the methylene chloride is distilled and recovered, and the colorless and transparent liquid is D (-) formyl mandelic acid chloride. The reaction is mild and environment-friendly, the reaction conversion rate and the product purity can be effectively improved, the production cost is effectively reduced, the operation is simple and convenient, and the industrial production is facilitated.
Spirocyclic Side-chain Derivatives of Penicillin and Cephalosporin
Sammes, Peter G.,Smith, Steven,Ross, Barry C.
, p. 2117 - 2124 (2007/10/02)
A series of two spirocyclic oxazolidinone derivatives of penicillin and four derivatives of cephalosporin have been prepared, as well as a benzoxazine conjugate of cephalosporin, with the object of freezing the conformation of the 6(7)-amide side-chain bearing a pendant aromatic ring.The antibacterial properties of these derivatives are discussed.