29171-20-8Relevant articles and documents
Quantitation of (R)- and (S)-Linalool in Beer Using Solid Phase Microextraction (SPME) in Combination with a Stable Isotope Dilution Assay (SIDA)
Steinhaus, Martin,Fritsch, Helge T.,Schieberle, Peter
, p. 7100 - 7105 (2003)
A stable isotope dilution assay (SIDA) was developed for the quantitation of both linalool enantiomers using synthesized [2H 2]R/S-linalool as the internal standard. For enrichment of the target compound from beer, a solid phase microextraction method (SPME) was developed. In comparison to the more time-consuming extraction/distillation cleanup of the beer samples, the results obtained by SPME/SIDA were very similar, even under nonequilibration conditions. Analysis of five different types of beer showed significant differences in the linalool concentrations, which were clearly correlated with the intensity of the hoppy aroma note as evaluated by a sensory panel. In addition, significant differences in the R/S ratios were measured in the beers. The SPME/SIDA yielded exact data independently from headspace sampling parameters, such as exposure time or ionic strength of the solution.
Acetylene method (by machine translation)
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Paragraph 0040-0053; 0060-0068, (2019/11/29)
In the presence of a catalyst alkoxide or an amino N,N - salt, the saturated or unsaturated ketone or aldehyde compound is subjected to acetylene hydrogenation to obtain the corresponding alkynol compound, and has the advantages of moderate reaction rate, mild reaction, easy control, easy separation of the product, recyclable solvent and the like. (by machine translation)
Method for efficiently preparing alkynol
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Paragraph 0036; 0037; 0038; 0043; 0044; 0045; 0046, (2018/12/14)
The invention relates to a method for efficiently preparing alkynol, belongs to the field of preparation of chemical intermediates and chemicals, and particularly relates to a preparation method of alkynol. The preparation method comprises the following steps that 1, alkali metal is added into an anhydrous alcohols solvent; an alcohol-alkali metal solution is prepared; 2, a compound I is added into the alcohol-alkali metal solution; uniform stirring is performed; cooling is performed to be 0 DEG C or below; 3, acetylene is introduced through being metered at normal pressure; alkynol is obtained; 4, the alkynol solution after reaction is neutralized by ammonium chloride and a same alcohol mixed suspension system; 5, the neutralized mixed suspension system is filtered; after alcohols are recovered from filter liquid, reduced pressure distillation is performed to obtain an alkynol product. The method overcomes the defect that under the existing harsh reaction conditions of high pressure,liquid ammonia and the like, the solid potassium hydroxide feeding difficulty is avoided; under the ordinary pressure condition, the ketone compounds are converted into alkynol at high conversion rate. The method has the advantages of high conversion rate, simple process and good product purity.
