292-45-5

Basic information

• Product Name: 1,2,4,6-Tetrathiepane
• Synonyms: 1,2,4,6-Tetrathiepane
• CAS NO: 292-45-5
• Molecular Formula: C₃H₆S₄
• Molecular Weight: 0
• Mol File: 292-45-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 307.4°C at 760 mmHg
• Flash Point: 157.2°C
• Appearance: /
• Density: 1.395g/cm³
• Vapor Pressure: 0.00131mmHg at 25°C
• Refractive Index: 1.686
• CAS DataBase Reference: 1,2,4,6-Tetrathiepane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4,6-Tetrathiepane(292-45-5)
• EPA Substance Registry System: 1,2,4,6-Tetrathiepane(292-45-5)

Safety Data

• Hazardous Substances Data: 292-45-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 22, p. 1939, 1981 DOI: 10.1016/S0040-4039(01)92873-4

InChI:InChI=1/C3H6S4/c1-4-2-6-7-3-5-1/h1-3H2

Upstream product

• 50-00-0 formaldehyd 
• 55-21-0 benzamide 
• 119-26-6 (2,4-dinitro-phenyl)-hydrazine 
• 18994-69-9 bis-chloromethyl disulfide 

Relevant articles and documents

Multicomponent heterocyclization of carboxamides with H2S and CH2O

Multicomponent heterocyclization of aliphatic amides with H2S and CH2O (1:3:2) in water-organic solvent mixture in the presence of BuONa led to the formation of 1,3,5-dithiazinane in high yield (30-95%) and with high selectivity (100%). Under these conditions benzamide gave 3,5-dibenzoyl-1,3,5-thiadiazinane in 74% yield, whereas due to ortho-effect the acetylsalicylamide with H2S and CH2O in a system BuOH-H2O without BuONa formed N-acetylsalicyloyl-1,3,5-dithiazinane (80%). Heterocyclization of α-aminosuccinic acid monoamide depending on the H2S and CH2O concentration occurred either at one or both NH2 yielding respectively mono-or bisdithiazinanes.

A simple, efficient synthesis of lenthionine and 1,2,4,6-tetrathiepane from dimethyl disulfide

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