29211-78-7

Basic information

• Product Name: 1,3-Dioxane,2,2-dimethyl-4-phenyl-(9CI)
• Synonyms: 1,3-Dioxane,2,2-dimethyl-4-phenyl-(9CI)
• CAS NO: 29211-78-7
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.25424
• Product Categories: PHENYL
• Mol File: 29211-78-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Dioxane,2,2-dimethyl-4-phenyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane,2,2-dimethyl-4-phenyl-(9CI)(29211-78-7)
• EPA Substance Registry System: 1,3-Dioxane,2,2-dimethyl-4-phenyl-(9CI)(29211-78-7)

Safety Data

• Hazardous Substances Data: 29211-78-7(Hazardous Substances Data)

Usage

Chemical class

Dioxane compounds, cyclic ethers

Physical state

Colorless, flammable liquid

Odor

Pleasant

Usage

Solvent in industrial and laboratory processes, synthesis of other organic compounds

Environmental impact

Potential environmental contaminant

Health risk

Human carcinogen

Regulatory status

Regulations and guidelines in place to limit use and exposure

Purpose of regulations

To protect human health and the environment

Upstream product

• 4850-49-1 1-phenyl-1,3-propanediol 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 122-97-4 3-Phenyl-1-propanol 
• 13133-97-6 2-methyl-3-phenylpentane-2,5-diol 

Relevant articles and documents

Direct Deamination of Primary Amines via Isodiazene Intermediates

We report here a reaction that selectively deaminates primary amines and anilines under mild conditions and with remarkable functional group tolerance including a range of pharmaceutical compounds, amino acids, amino sugars, and natural products. An anomeric amide reagent is uniquely capable of facilitating the reaction through the intermediacy of an unprecedented monosubstituted isodiazene intermediate. In addition to dramatically simplifying deamination compared to existing protocols, our approach enables strategic applications of iminium and amine-directed chemistries as traceless methods. Mechanistic and computational studies support the intermedicacy of a primary isodiazene which exhibits an unexpected divergence from previously studied secondary isodiazenes, leading to cage-escaping, free radical species that engage in a chain, hydrogen-atom transfer process involving aliphatic and diazenyl radical intermediates.