29211-87-8Relevant academic research and scientific papers
Solvent-free iron(III) chloride-catalyzed direct amidation of esters
Mkhonazi, Blessing D.,Shandu, Malibongwe,Tshinavhe, Ronewa,Simelane, Sandile B.,Moshapo, Paseka T.
supporting information, (2020/03/17)
Amide functional groups are prominent in a broad range of organic compounds with diverse beneficial applications. In this work, we report the synthesis of these functional groups via an iron(iii) chloride-catalyzed direct amidation of esters. The reactions are conducted under solvent-free conditions and found to be compatible with a range of amine and ester substrates generating the desired amides in short reaction times and good to excellent yields at a catalyst loading of 15 mol%.
Highly chemoselective, sterically sensitive NHC-catalysed amine acylation with pyridil
Maguire, Amy C.,Kumar, Vikas,Connon, Stephen J.
supporting information, p. 13526 - 13529 (2019/11/14)
A new strategy for the protection of amines has been developed involving reaction with pyridil under the influence of N-heterocyclic carbene catalysis. The methodology is capable of distinguishing between two amines characterised by small differences in steric bulk and the resulting pyridoyl amides can be cleaved without requiring either strongly acidic or basic hydrolysis.
Lanthanum(III) triflate catalyzed direct amidation of esters
Morimoto, Hiroyuki,Fujiwara, Risa,Shimizu, Yuhei,Morisaki, Kazuhiro,Ohshima, Takashi
supporting information, p. 2018 - 2021 (2014/05/06)
Lanthanum trifluoromethanesulfonate is an effective single-component catalyst for synthesizing a variety of amides directly from esters and amines under mild conditions. Highly selective amidation of esters and amines, as well as catalyst-controlled amidation of esters, demonstrated the effectiveness of the catalyst system.
Catalytic transamidation reactions compatible with tertiary amide metathesis under ambient conditions
Stephenson, Nickeisha A.,Zhu, Jiang,Gellman, Samuel H.,Stahl, Shannon S.
experimental part, p. 10003 - 10008 (2009/12/08)
The carbon-nitrogen bond of carboxamides is extremely stable under most conditions. The present study reveals that simple zirconium- and hafnium-amido complexes are highly efficient catalysts for equilibrium-controlled transamidation reactions between sec
