292155-95-4Relevant academic research and scientific papers
Synthesis of triazolopyridines as conformationally constrained tertiary amides
Lawson, Edward C.,Maryanoff, Bruce E.,Hoekstra, William J.
, p. 4533 - 4536 (2000)
Amide derivatives of cyclic amines are common templates for biologically active chemical entities. To constrain the tertiary amide moiety of N- acylpiperidine-based GPIIb/IIIa antagonists for further structure-activity study, we have prepared new 1,2,4-triazolo[4,3-a]pyridines. The syntheses of two classes of triazolopyridines are reported. (C) 2000 Elsevier Science Ltd.
SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF
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Page/Page column 99, (2019/05/15)
Substituted triazole derivatives and uses thereof The present invention relates to novel substituted 1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.
SUBSTITUTED TRIAZOLOPYRIDINES AND ANALOGS THEREOF
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Page/Page column 23-24, (2010/11/03)
The present invention relates to substituted triazolopyridines and analogs thereof, the use of the compounds as phosphodiesterase 10 (PDE10) inhibitors for the treatment of PDE10-modulated disorders, to pharmaceutical compositions comprising the compounds.
