2922-94-3

Basic information

• Product Name: cytidine 3',5'-diphosphate
• Synonyms: cytidine 3',5'-diphosphate
• CAS NO: 2922-94-3
• Molecular Formula: C₉H₁₅N₃O₁₁P₂
• Molecular Weight: 403.176422
• Mol File: 2922-94-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 811.1°Cat760mmHg
• Flash Point: 444.3°C
• Appearance: /
• Density: 2.35g/cm³
• CAS DataBase Reference: cytidine 3',5'-diphosphate(CAS DataBase Reference)
• NIST Chemistry Reference: cytidine 3',5'-diphosphate(2922-94-3)
• EPA Substance Registry System: cytidine 3',5'-diphosphate(2922-94-3)

Safety Data

• Hazardous Substances Data: 2922-94-3(Hazardous Substances Data)

Upstream product

• 90907-24-7 2'-O-t-butyldimethylsilylcytidylyl (3'-> 5') adenosine 5'-monophosphate 
• 15648-73-4 cytidylyl (3'-> 5') adenosine 5'-monophosphate 
• 63-37-6 cytidine monophosphate 

Relevant articles and documents

Phosphorylation of Nucleotides with Inorganic Cyclo-Triphosphate

Phosphorylation of nucleotides (nucleoside 3'- and 5'-monophosphates, and 2'-deoxynucleoside 5'-monophosphates) with inorganic sodium cyclotriphosphate (P3m) was studied in aqueous solutions under various conditions (mixing ratio of P3m to nucleotides, pH, reaction temperature, and time). (1) Unprotected nucleoside 5'-monophosphates (5'-NMP's) were easily phosphorylated at the cis-2',3'-diol by P3m to form selectively nucleoside 2',5'-bis(monophosphate) (2',5'-NDP's), nucleoside 3',5'-bis(monophosphate) (3',5'-NDP's), and nucleoside 2',3'-cyclic 5'-bis(monophosphate) (cNDP's). (2) The phosphorylation of 5'-NMP's was strongly dependent on mixing ratio, pH, reaction temperature, and time.Under conditions of high mixing ratios of P3m to 5'-NMP's (5:1 - 10:1), high pH (12), and room temperature, 92 -98percent of 5'-NMp's was converted into 3',5'-NDP's and 2',5'-NDP's in roughly equimolar quantities. (3) Small quantities (5 -8percent) of cNdP's were formed at the initial stage of reaction of 5'-NMP's with P3m but in the course of the reaction for a long period, cNDP's were hydrolyzed to 2',5'-NDP's and 3',5'-NDP's. (4) Nucleoside 3'-monophosphates (3'-NMP's) and 2'-deoxynucleoside 5'-monophosphates (dNMP's) could not be phosphorylated by P3m, which indicates that the presence of hydroxyl groups at both 2'- and 3'-positions on nucleotides is indispensable for the phosphorylation of nucleotides with P3m. (5) The mechanism of the formation of 2',5'-NDP's, 3',5'-NDP's, and cNDP's in the phosphorylation of 5'-NMP's with P3m is discussed.

The reaction of phenylboronic acid with nucleosides and mononucleotides.

-