29228-83-9

Basic information

• Product Name: 6-methyl-5-(piperidin-1-ylmethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
• CAS NO: 29228-83-9
• Molecular Formula: C₁₁H₁₇N₃OS
• Molecular Weight: 239.3372
• Mol File: 29228-83-9.mol
• Article Data: 2

Chemical Properties

• Density: 1.25g/cm³
• Refractive Index: 1.619
• CAS DataBase Reference: 6-methyl-5-(piperidin-1-ylmethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-5-(piperidin-1-ylmethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one(29228-83-9)
• EPA Substance Registry System: 6-methyl-5-(piperidin-1-ylmethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one(29228-83-9)

Safety Data

• Hazardous Substances Data: 29228-83-9(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 56-04-2 6-methyl-2-thiouracil 
• 50-00-0 formaldehyd 
• 56-04-2 2-mercapto-6-methylpyrimidin-4(3H)-one 

Relevant articles and documents

A practical synthesis and spectroscopic study of new potentially biologically active S-lithocholic acid-substituted derivatives of 2-thiouracil

Five new S-3α-acetoxy-5β-lithocholic acid methyl ester-substituted derivatives of 2-thiouracil and 6-methyl-2-thiouracil have been prepared. 5-Morpholino-methyl-2-thiouracil, 5-piperidinomethyl-2- thiouracil, and 5-(4-methylpiperidino)methyl-2-thiouracil have been obtained via the Mannich reaction between 6-methyl-2-thiouracil, paraformaldehyde, and the cyclic secondary amines morpholine, piperidine, or 4-methylpiperidine in ethanol. The structures of the compounds were confirmed by spectral ( 1H NMR, 13C NMR, and FT-IR) analyses and mass spectrometry. Estimation of the pharmacotherapeutic potential has been accomplished for the synthesized compounds on the basis of Prediction of Activity Spectra for Substances (PASS).