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Ethyl 4-hydrazino-2-(trifluoromethyl)pyrimidine-5-carboxylate is a chemical compound with the molecular formula C7H8F3N3O2. It is a derivative of pyrimidine, a heterocyclic aromatic organic compound consisting of a six-membered ring with four carbon atoms and two nitrogen atoms. The compound features a trifluoromethyl group (-CF3) at the 2-position, a hydrazino group (-NHNH2) at the 4-position, and a carboxylate group (-COO-) at the 5-position. This molecule is an ester, formed by the reaction of the carboxylic acid group with ethanol. It is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly those involving pyrimidine-based structures. Due to its reactivity and potential applications, it is important to handle ETHYL 4-HYDRAZINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE with care, following appropriate safety protocols.

2924-82-5

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2924-82-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2924-82-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,2 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2924-82:
(6*2)+(5*9)+(4*2)+(3*4)+(2*8)+(1*2)=95
95 % 10 = 5
So 2924-82-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H9F3N4O2/c1-2-17-6(16)4-3-13-7(8(9,10)11)14-5(4)15-12/h3H,2,12H2,1H3,(H,13,14,15)

2924-82-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 4-hydrazino-2-(trifluoromethyl)-5-pyrimidinecarboxylate

1.2 Other means of identification

Product number -
Other names ethyl 4-hydrazino-2-trifluoromethylpyrimidine-5-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2924-82-5 SDS

2924-82-5Downstream Products

2924-82-5Relevant academic research and scientific papers

Novel inhibitors of AP-1 and NF-κB mediated gene expression: Structure-activity relationship studies of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimidine-5-carb oxylate

Palanki, Moorthy S.S.,Erdman, Paul E.,Manning, Anthony M.,Ow, Arnold,Ransone, Lynn J.,Spooner, Cheryl,Suto, Carla,Suto, Mark

, p. 1645 - 1648 (2007/10/03)

In an effort to identify novel inhibitors of AP-1 and NF-κB mediated transcriptional activation, several analogues of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimidine-5-carb oxylate (1) were synthesized and tested in two in vitro assays. The 2-(2'-thienyl) substituted compound (11) was identified as the most potent in this series. (C) 2000 Elsevier Science Ltd. All rights reserved.

Pyrimidine carboxylates and related compounds and methods for treating inflammatory conditions

-

, (2008/06/13)

Compounds having utility as anti-inflammatory agents in general and, more specifically, for the prevention and/or treatment of immunoinflammatory and autoimmune diseases are disclosed. The compounds are pyrimidine-containing compounds and, in one embodiment, are esters of the same. Methods are also disclosed for preventing and/or treating inflammatory conditions by administering to an animal in need thereof an effective amount of a compound of this invention, preferably in the form of a pharmaceutical composition.

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