29241-16-5

Usage

InChI:InChI=1/C6H3N3O2S/c10-9(11)4-1-2-5-6(3-4)12-8-7-5/h1-3H

Upstream product

• 23451-98-1 2-amino-5-nitrobenzenethiol 
• 2942-06-5 6-nitrobenzo[d]thiazole 
• 58381-87-6 2-[(2-amino-5-nitrophenyl)dithio]-4-nitrophenylamine 

Downstream Products

• 41972-62-7 benzo[d][1,2,3]thiadiazol-6-amine 
• 1371608-80-8 (R)-1-(benzo[d][1,2,3]thiadiazol-6-yl)-5-(trityloxymethyl)pyrrolidin-2-one 
• 1426152-53-5 1-(benzo[d][1,2,3]thiadiazol-6-yl)-3-(2-oxo-2-(piperidin-1-yl)ethyl)urea 
• 1426152-52-4 C₁₅H₁₁FN₄O₂S 
• 1426152-51-3 C₁₅H₁₈N₄O₂S 
• 1426152-50-2 C₁₅H₂₀N₄O₂S 
• 1426152-49-9 C₁₅H₁₃FN₄O₂S 
• 1426152-48-8 C₁₅H₁₃FN₄O₂S 
• 1426152-47-7 C₁₅H₁₂F₂N₄OS 
• 1426152-46-6 C₁₅H₁₄N₄O₂S 
• 1426152-75-1 C₁₆H₁₅FN₄OS 
• 1426152-74-0 C₁₅H₁₂N₄O₂S 
• 1426152-73-9 C₁₅H₁₁F₃N₄OS 
• 1426152-72-8 C₁₄H₁₁FN₄OS 

Relevant academic research and scientific papers

Histone lysine methyltransferase NSD2 inhibiting small-molecule compound and application thereof

The invention belongs to the field of chemical medicine and particularly relates to a histone lysine methyltransferase NSD2 inhibiting small-molecule compound. A general formula of the small-moleculecompound is as shown in the specification. According to

Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors

Protein arginine methyltransferases (PRMTs) play an important role in diverse biological processes. Among the nine known human PRMTs, PRMT3 has been implicated in ribosomal biosynthesis via asymmetric dimethylation of the 40S ribosomal protein S2 and in c

SELECTIVE ANDROGEN RECEPTOR MODULATORS

This invention provides compounds of formula I, pharmaceutical compositions comprising a compound of formula I and a pharmaceutically acceptable excipient, methods of modulating the androgen receptor, methods of treating diseases beneficially treated by an androgen receptor modulator (e.g., sarcopenia, prostate cancer, contraception, type 2 diabetes related disorders or diseases, anemia, depression, and renal disease) and processes for making compounds and intermediates useful in the preparation of same.

Efficient solid phase synthesis of benzo[1,2,3]thiadiazoles and related structures

The first solid-phase synthesis of benzo[1,2,3]thiadiazoles was achieved by starting from resin bound ortho bromo or iodo triazenes and using a functionalization on cleavage. Two different synergistic methods including an anionic approach and a cross-coupling approach were used for the synthesis. The resulting diazonium compounds readily underwent electrophilic cyclization yielding benzothiadiazoles, when cleaving the arenethiol resins. Cleavage from the resin with diluted trifluoroacetic acid resulted spontaneously in the desired cyclization reaction.