29248-42-8

Basic information

• Product Name: 4-methyl-1,2-dihydrobenzo[f]isoquinoline
• Synonyms: Benz[f]isoquinoline, 1,2-dihydro-4-methyl-
• CAS NO: 29248-42-8
• Molecular Formula: C₁₄H₁₃N
• Molecular Weight: 195.2597
• Mol File: 29248-42-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 103 °C(Solv: acetone (67-64-1))
• Boiling Point: 340.6°C at 760 mmHg
• Flash Point: 151.9°C
• Density: 1.1g/cm³
• Vapor Pressure: 0.000168mmHg at 25°C
• Refractive Index: 1.624
• PKA: 5.96±0.20(Predicted)
• CAS DataBase Reference: 4-methyl-1,2-dihydrobenzo[f]isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-1,2-dihydrobenzo[f]isoquinoline(29248-42-8)
• EPA Substance Registry System: 4-methyl-1,2-dihydrobenzo[f]isoquinoline(29248-42-8)

Safety Data

• Hazardous Substances Data: 29248-42-8(Hazardous Substances Data)

Upstream product

• 86-87-3 naphth-1-yl acetic acid 
• 773-99-9 2-naphthaleneethanol 
• 75-05-8 acetonitrile 

Downstream Products

• 110229-22-6 4-Dicyanomethylen-2,3-diphenyl-8,9-benzo-4H-2,3,6,7-tetrahydropyridno<2.1-a>isochinolin 
• 110229-39-5 4-(1,3-Dioxoindan-2-yliden)-2,3-diphenyl-8,9-benzo-4H-6,7-dihydropyridino<2.1-a>isochinolin 
• 110229-38-4 4-(1,3-Dioxoindan-2-yliden)-2,3-diphenyl-8,9-benzo-4H-2,3,6,7-tetrahydropyridino<2.1-a>isochinolin 
• 108201-00-9 10b-Methyl-2,3-diphenyl-1-oxo-1,5,6,10b-tetrahydro-7,8-benzopyrrolo<2.1-a>isochinolin 
• 108201-02-1 10b-Methyl-2,3-diphenyl-1-thioxo-1,5,6,10b-tetrahydro-7,8-benzopyrrolo<2.1-a>isochinolin 
• 110229-27-1 2,3-Diphenyl-8,9-benzo-1,2,3,4,6,7,11b-heptahydropyridino<2.1-a>isochinolin 
• 110229-24-8 4-Dicyanomethylen-2,3-diphenyl-8,9-benzo-4H-6,7-dihydropyridino<2.1-a>isochinolin 
• 110229-33-9 4-Dicyanomethylen-2,3-diphenyl-8,9-benzo-4H-pyridino<2.1-a>isochinolin 
• 110229-32-8 4-Oxo-2,3-diphenyl-8,9-benzo-4H-pyridino<2.1-a>isochinolin 

Relevant articles and documents

Construction of a Protoberberine Alkaloid Skeleton via the Palladium-Catalyzed α-Arylation–Amide Formation Cascade

In this work, we report the strategy of one-pot synthesis of protoberberine alkaloid derivatives via palladium-catalyzed cascade α-arylation and cyclization, which can afford the target molecules in moderate to excellent isolated yields using commercially available raw materials under solvent-free conditions. This protocol provides an efficient and convenient path to multisubstituted protoberberine derivatives. In addition, it can directly afford natural alkaloids.