292609-33-7Relevant academic research and scientific papers
Synthesis of benzolactams by 11-endo selective aryl radical cyclisation of 2-iodobenzamides
Prado, Maria A.F.,Alves, Ricardo J.,Souza Jr., Jose D.,Alves, Rosemeire B.,Pedrosa, Maria T.C.,Prado, Renata F.,Faraco, Andre A.G.
, p. 1853 - 1857 (2007/10/03)
Regioselective 11-endo aryl radical cyclisation of methyl 4-O-allyl-2,3-di-O-benzyl-6-deoxy-6-(2-iodobenzoylamino)-α-D- glucopyranoside 4 and N-(3-allyloxypropyl)-2-iodobenzamide 9 with tri-n-butyltin hydride provided the benzolactams 5 and 10, respectively. The unequivocal structures of 5 and 10 were supported by 1H and 13C NMR spectroscopy and by PENDANT or DEPT, COSY and HMQC experiments. The Royal Society of Chemistry 2000.
