292636-13-6

Basic information

• Product Name: 1H-Indol-7-amine,4-fluoro-(9CI)
• Synonyms: 1H-Indol-7-amine,4-fluoro-(9CI);1H-Indol-7-aMine, 4-fluoro-;7-AMino-4-fluoroindole;4-Fluoro-1H-indol-7-amine;4-Fluoro-1H-indol-7-ylamine
• CAS NO: 292636-13-6
• Molecular Formula: C₈H₇FN₂
• Molecular Weight: 150.155
• Product Categories: AMINEPRIMARY;INDOLE;HALIDE
• Mol File: 292636-13-6.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 1H-Indol-7-amine,4-fluoro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indol-7-amine,4-fluoro-(9CI)(292636-13-6)
• EPA Substance Registry System: 1H-Indol-7-amine,4-fluoro-(9CI)(292636-13-6)

Safety Data

• Hazardous Substances Data: 292636-13-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1H-Indol-7-amine,4-fluoro-(9CI) is used as a key intermediate in the synthesis of pharmaceutical drugs for its unique chemical properties and potential biological activities. Its structure allows for further functionalization and modification to develop new drug candidates with improved pharmacological profiles.
Used in Agrochemical Industry:
1H-Indol-7-amine,4-fluoro-(9CI) is used as a building block in the development of agrochemicals, such as pesticides and herbicides, due to its reactivity and potential to interact with biological targets. Its unique structure may contribute to the discovery of novel agrochemicals with enhanced efficacy and selectivity.
Used in Synthetic Organic Chemistry Research:
1H-Indol-7-amine,4-fluoro-(9CI) serves as an interesting target for synthetic organic chemistry research, providing opportunities to explore new synthetic routes, reactions, and transformations. Its unique chemical properties and reactivity can be harnessed to develop innovative synthetic strategies and methodologies.
Used in Medicinal Chemistry Research:
1H-Indol-7-amine,4-fluoro-(9CI) is utilized in medicinal chemistry research to investigate its potential as a lead compound for the development of new therapeutic agents. Its structure and reactivity can be optimized to enhance its pharmacological properties, such as potency, selectivity, and bioavailability, leading to the discovery of novel drugs with improved therapeutic profiles.
Further studies are required to fully understand the potential uses and properties of 1H-Indol-7-amine,4-fluoro-(9CI), as well as to explore its applications in various industries and research fields.

Upstream product

• 446-09-3 2-bromo-5-fluoronitrobenzene 
• 292636-09-0 7-bromo-4-fluoro-1H-indole 

Downstream Products

• 292636-22-7 N-(3-chloro-4-fluoro-1H-indol-7-yl)-4-nitro-benzenesulfonamide 
• 292636-23-8 N-(4-fluoro-1H-indol-7-yl)-4-nitro-benzenesulfonamide 

Relevant articles and documents

A focused compound library of novel N-(7-indolyl)benzenesulfonamides for the discovery of potent cell cycle inhibitors

A series of compounds containing an N-(7-indolyl)benzenesulfonamide pharmacophore was synthesized and evaluated as a potential antitumor agent. Cell cycle analysis with P388 murine leukemia cells revealed that there were two different classes of potent cell cycle inhibitors; one disrupted mitosis and the other caused G1 accumulation. Herein described is the SAR summary of the substituent patterns on this pharmacophore template. (C) 2000 Elsevier Science Ltd. All rights reserved.