292641-71-5

Basic information

• Product Name: ethyl 2-(4-hydroxybenzylidene)-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
• Synonyms: ethyl 2-(4-hydroxybenzylidene)-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
• CAS NO: 292641-71-5
• Molecular Formula: C24H22N2O4S2
• Molecular Weight: 466.57248
• Mol File: 292641-71-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 2-(4-hydroxybenzylidene)-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(4-hydroxybenzylidene)-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate(292641-71-5)
• EPA Substance Registry System: ethyl 2-(4-hydroxybenzylidene)-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate(292641-71-5)

Safety Data

• Hazardous Substances Data: 292641-71-5(Hazardous Substances Data)

Upstream product

• 292871-44-4 ethyl 4-[4-(methylthio)phenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 123-08-0 4-hydroxy-benzaldehyde 
• 79-11-8 chloroacetic acid 
• 3446-89-7 4-(Methylthio)benzaldehyde 
• 141-97-9 ethyl acetoacetate 

Relevant articles and documents

Convenient one pot synthesis of some novel derivatives of thiazolo[2,3-b]dihydropyrimidinone possessing 4-methylthiophenyl moiety and evaluation of their antibacterial and antifungal activities

A series of new 2-(arylidene/5-arylfurfurylidene)-5-(4-methylthiophenyl)-6-carbethoxy-7- methyl-5H-thiazolo[2,3-b]pyrimidin-3(1H)-ones 2 and 3 have been synthesized by a three component (MCR) reaction involving 4-(4-methylthiophenyl)-5-carbethoxy-6-methyl-3,4-dihydropyrimidin-2(1H)- thione 1, monochloroacetic acid and arylaldehydes/arylfurfuraldehydes, respectively. The newly synthesized compounds were well characterized by elemental analysis, IR, 1H NMR and mass spectral studies. The newly synthesized compounds were screened for their antibacterial and antifungal activities and have exhibited moderate to excellent growth inhibition of bacteria and fungi. The results of such studies have been discussed in this paper.