292819-39-7Relevant academic research and scientific papers
Preparation method of furan macrocyclic compound, prepared furan macrocyclic compound and application of furan macrocyclic compound
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Paragraph 0217-0221, (2021/08/07)
The invention discloses a preparation method of a furan macrocyclic compound, the prepared furan macrocyclic compound and application of the furan macrocyclic compound. According to the preparation method disclosed by the invention, a macrocyclic alkyne olefine aldehyde compound is used as a raw material and is subjected to cyclization reaction under the catalysis of metal. The preparation method disclosed by the invention is simple to operate, simple and convenient in steps and high in efficiency, and the atom utilization rate is up to 100%. The reaction raw material macrocyclic alkyne olefine aldehyde compound can be obtained by a cyclic ketone compound or an alkyl alcohol compound through several steps of reaction with mature process and very high efficiency. The furan macrocyclic compound with a brand-new and special structure is obtained by the method, can be used as an element unit to synthesize a series of oligomerization furan compounds, and has potential optical application value.
Solid-phase synthesis of hydroxy-acids leading to macrolactones
Gagnon, René,Dory, Yves L.,Deslongchamps, Pierre
, p. 4751 - 4755 (2007/10/03)
A sequence of five chemical steps on solid support yields hydroxy-acids in a very straightforward and efficient manner. The resulting compounds can be cyclized in solution phase by forming an ester bond to produce macrolactones. (C) 2000 Published by Elsevier Science Ltd.
