292852-18-7Relevant academic research and scientific papers
One-pot multicomponent synthesis hexahydroquinoline derivatives in Triton X-100 aqueous micellar media
Poor Heravi, Mohammad Reza,Mehranfar, Shadi,Shabani, Nemat
, p. 141 - 145 (2014)
A facile and efficient synthesis of hexahydroquinoline derivatives (5a-o) was reported via a four-component condensation reaction of aldehydes, dimedone, methyl aceto acetate and ammonium acetate in the presence of Triton X-100 in water at room temperature. The use of just 20 mol % of Triton X-100 in water solvent is sufficient. The FT-IR, 19F NMR, 1H NMR, 13C NMR spectra and elemental analysis confirm the structure of the compounds.
Cobalt triflate catalyzed one-pot synthesis of fluorophore 1,4-dihydropyridine derivatives via Hantzsch reaction
Bagdi, Prasanta Ray,Basha, R. Sidick,Lal, Mohan,Misra, Rajkumar,Khan, Abu T.
, p. 1589 - 1598 (2014/01/17)
A wide variety of 1,4-dihydropyridines have been synthesized through one-pot condensation of aromatic aldehydes, β-ketoesters, cyclic 1,3-diones and ammonium acetate using cobalt triflate as a catalyst through Hantzsch reaction. Some of the salient features of the present protocol are shorter reaction time, mild reaction conditions, good yields, non-aqueous work-up, reusability of the catalyst and non-requirement of column chromatographic separation.
