292852-45-0

Upstream product

• 141-97-9 ethyl acetoacetate 
• 17356-08-0 thiourea 
• 613-45-6 2,4-Dimethoxybenzaldehyde 

Downstream Products

• 1149335-26-1 5-ethoxycarbonyl-6-methyl-4-(2,4-dimethoxyphenyl)-2-(2-hydroxy-2-phenylvinyl)-1,4-dihydropyrimidine 
• 350047-05-1 ethyl 5-(2,4-dimethoxyphenyl)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate 
• 1315248-19-1 ethyl 3-methyl-5-(2,4-dimethoxyphenyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate 
• 1341227-67-5 4-(2,4-dimethoxyphenyl)-6-methyl-3-(N-cytisinomethyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester 
• 1084955-63-4 C₃₂H₂₈N₄O₆ 

Relevant academic research and scientific papers

Synthesis and in vitro antimicrobial studies of thiodihydropyrimidine derivatives

In the present study, a series of thiodihydropyrimidine derivatives were synthesized from different substituted aromatic aldehydes, ethyl acetoacetate, and urea/thiourea using a bimetallic TUD-1 catalyst. The structures of all the synthesized compounds we

H2so4-silica catalyzed one-pot and efficient synthesis of dihydropyrimidinones under solvent-free conditions

H2SO4-Silica efficiently catalyzes the three-component condensation reaction of aldehydes, 1,3-dicarbonyl compounds and urea/thiourea under solvent free conditions to afford the corresponding dihydropyrimidinones and thio-derivatives

An efficient one-pot synthesis of dihydropyrimidinones catalyzed by zirconium hydrogen phosphate under solvent-free conditions

A simple, efficient, and practical procedure for the Biginelli reaction using zirconium hydrogen phosphate [Zr(H2 PO4) 2] as a novel solid acid catalyst is described under solvent-free conditions in high yields. The cataly

Synthesis and inhibitory activity against Epstein-Barr virus of some new 1,2,3,4-tetrahydropyrimidine-2-thiones

1,2,3,4-Tetrahydropyrimidine-2-thiones 4a-n were synthesized through the reaction of aromatic aldehydes 1a-n, ethyl acetoacetate (2) and thiourea (3). The structures of all newly synthesized heterocyclic compounds elucidated by the use of IR, 1H NMR, mass

New catalysts of Biginelli reaction

A synthesis was developed of new imidazole derivatives catalyzing three-component condensation of ethyl acetoacetate, aromatic aldehydes, and urea(or thiourea) by Biginelli reaction.